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User:Hannah Luchinski/Sandbox 1
From Proteopedia
proteopedia linkproteopedia link Human Neurofibromin, 7PGR
Figure 1. The coolest image of this protein EVAH!!!
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Introduction
Neurofibromin is a tumor suppressor protein that is coded for by the Neurofibromin 1 gene.
Function
[1]
Structural highlights
Closed Conformation
Zinc Stabilized Transition Metal Binding Site
Open Conformation
Sec14-PH and GRD Domains
Arginine Finger
Disease
Relevance
[2]
Student Contributors
- Hannah Luchinski
- Sophie Mullinix
This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
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References
- ↑ Bergoug M, Doudeau M, Godin F, Mosrin C, Vallee B, Benedetti H. Neurofibromin Structure, Functions and Regulation. Cells. 2020 Oct 27;9(11). pii: cells9112365. doi: 10.3390/cells9112365. PMID:33121128 doi:http://dx.doi.org/10.3390/cells9112365
- ↑ Ransey E, Paredes E, Dey SK, Das SR, Heroux A, Macbeth MR. Crystal structure of the Entamoeba histolytica RNA lariat debranching enzyme EhDbr1 reveals a catalytic Zn(2+) /Mn(2+) heterobinucleation. FEBS Lett. 2017 Jul;591(13):2003-2010. doi: 10.1002/1873-3468.12677. Epub 2017, Jun 14. PMID:28504306 doi:http://dx.doi.org/10.1002/1873-3468.12677
