User:Rafael Almeida Gomes/Sandbox 1
From Proteopedia
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Silk fibers from Bombyx mori have been utilized by mankind since ancient times due to its remarkable mechanical properties and comfort when woven into fabrics, its earliest record being around 2.700 BC. It is thermally comfortable, elastic, strong and soft and that is why it is highly sought after as a luxury fabric for garments. It is also biocompatible, making it even applicable as a medical biomaterial for sutures or scaffolds. Bombyx mori silkworms naturally use their silk to construct a cocoon at the end of the final stage of larval development before cocoon formation, before they undergo metamorphosis into a moth. During the natural spinning process, the silkworm extrudes the silk dope (a water-soluble liquid crystalline state containing up to 30%wt/vol fibroin in water) from its spinnerets into the external environment. This process involves mechanical shearing, stretching, and water evaporation. The delicate gland conditions (silk dope acidification, concentration changes of metal ions, and water content reduction) are crucial for the proper folding of fibroin into micelles and then liquid crystals.
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