User talk:Wayne Chang

From Proteopedia

Welcome to Proteopedia! We hope you will contribute much and well. You will probably want to read the help pages. Again, welcome and have fun! Eran Hodis 03:55, 15 October 2008 (IST)

Comments on your Outline

Comment
Assignment 12: IVC: Ammonium Binding Site: Map the Ammonium binding site and explain how it contributes to cataysis.[9]
1. First paragraph, drop the human reference, not relevant.
2. Use subscripts and superscripts.
3. Make sure the equation is balance by charge.
4. The structure is not arranged as two face-to-face benzene rings; try again. .
5. Use the angstrom symbol and you used a O instead of a 0. .
6. Use the reference format I use in my page. .
7. Glutamate has the highly negative carboxyl group which may directly interact with the positively charged ion due to its flexible side chain (Liaw et al., 1995). Are you sure that Liaw stated this, since glu binds first and then it is phosphoryated before ammonia interacts with the enzyme, so I thought.
8. Which glutamate are you talking about be clear. You can use more WIKI applets to illustrate your points.
9. A deprotonated ammonia completes the reaction after an ammonium ion binds to the negatively charged pocket of GS (Liaw et al., 1995) this sentence is awkward.
10. Please schedule an appointment.
8.5/9

Dr. Gluick

Final Comments

This is a pretty good job with a little more work you would have a great project. Unfortunately, there are a few mistakes marring your work. The language used in the first line of the first paragraph is incorrect. I am not sure how the first WIKI contributes to the overall project--it does not do much. In the second paragraph it is not clear what you are trying to accomplish. You show the ligands in the active site, but do not really tell the reader what they are seeing or what to look for. You make a valiant attempt showing the funnel. I am confused about the legend--it does not seem to correspond to anything in the WIKI. The third paragraph is done well.

Grade: 8.5/10

Dr. Gluick Tom Gluick 03:56, 21 December 2008 (IST)