RNA Interference

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*[[:Category:Rnai_suppression|RNAi Suppression]]
*[[:Category:Rnai_suppression|RNAi Suppression]]
*[[:Category:Rna interference|RNA Interference]]
*[[:Category:Rna interference|RNA Interference]]
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*[[:Category:Risc|RISC]]
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*[[:Category:Argonaute|Argonaute]]
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*[[:Category:Slicer|Slicer]]
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*[[:Category:Piwi|Piwi]]
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To view other Proteopedia pages about diseases & drug targets, See: [[Pharmaceutical_Drug_Targets|Pharmaceutical Drug Targets]]
To view other Proteopedia pages about diseases & drug targets, See: [[Pharmaceutical_Drug_Targets|Pharmaceutical Drug Targets]]

Revision as of 19:22, 26 September 2010

Schematic of RNAi Interference in Mammalian Cells
Schematic of RNAi Interference in Mammalian Cells

RNA Interference (RNAi) is a system in living cells that helps control the level of activity of genes. In RNAi, a long double stranded RNA is cleaved into shorter strands. One strand known as the guide strand is complimentary to the mRNA gene product of a gene of interest. This guide strand is incorporated into an RNA-induced silencing complex (RISC) and subsequently binds the mRNA of the gene of interest. After binding, the RNA/RISC complex subsequently silences the mRNA of interest via cleavage of the mRNA strand.

Articles in Proteopedia concerning RNA Interference include:


To view automatically seeded pages concerning RNA Interference See:


To view other Proteopedia pages about diseases & drug targets, See: Pharmaceutical Drug Targets

Proteopedia Page Contributors and Editors (what is this?)

David Canner, Wayne Decatur, Eric Martz

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