RNA Interference

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Articles in Proteopedia concerning RNA Interference include:
Articles in Proteopedia concerning RNA Interference include:
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*[[Suppression of RNA Silencing by Viruses|Suppression of RNA Silencing by Viruses]]
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**[[Suppression of RNA Silencing by Viruses|Suppression of RNA Silencing by Viruses]]
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*[[Plant_Viral_Protein_p19_Suppression_of_RNA_Silencing|Plant Viral Protein p19 Supression of RNA Silencing]]
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**[[Plant_Viral_Protein_p19_Suppression_of_RNA_Silencing|Plant Viral Protein p19 Supression of RNA Silencing]]
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*[[Tomato aspermy virus protein 2b Suppression of RNA Silencing|Tomato aspermy virus protein 2b Suppression of RNA Silencing]]
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**[[Tomato aspermy virus protein 2b Suppression of RNA Silencing|Tomato aspermy virus protein 2b Suppression of RNA Silencing]]
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*[[Flock house virus B2 protein Suppression of RNA Silencing|Flock house virus B2 protein Suppression of RNA Silencing]]
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**[[Flock house virus B2 protein Suppression of RNA Silencing|Flock house virus B2 protein Suppression of RNA Silencing]]
<br />
<br />
To view automatically seeded indices concerning RNA Interference See:
To view automatically seeded indices concerning RNA Interference See:
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*[[:Category:Argonaute|Argonaute]]
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**[[:Category:Argonaute|Argonaute]]
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*[[:Category:Dicer|Dicer]]
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**[[:Category:Dicer|Dicer]]
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*[[:Category:Drosha|Drosha]]
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**[[:Category:Drosha|Drosha]]
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*[[:Category:Piwi|Piwi]]
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**[[:Category:Piwi|Piwi]]
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*[[:Category:Risc|RISC]]
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**[[:Category:Risc|RISC]]
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*[[:Category:Rnai|RNAi]]
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**[[:Category:Rnai|RNAi]]
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*[[:Category:Rnai_suppression|RNAi Suppression]]
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**[[:Category:Rnai_suppression|RNAi Suppression]]
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*[[:Category:Rna interference|RNA Interference]]
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**[[:Category:Rna interference|RNA Interference]]
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*[[:Category:Slicer|Slicer]]
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**[[:Category:Slicer|Slicer]]
<br />
<br />
To view other Proteopedia pages about diseases & drug targets, See: [[Pharmaceutical_Drug_Targets|Pharmaceutical Drug Targets]]
To view other Proteopedia pages about diseases & drug targets, See: [[Pharmaceutical_Drug_Targets|Pharmaceutical Drug Targets]]

Revision as of 08:58, 27 September 2010

Schematic of RNAi Interference in Mammalian Cells
Schematic of RNAi Interference in Mammalian Cells

PDB ID 3dlh

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guide-strand-containing Argonaute protein silencing complex (3dlh), resolution 3.00Å ()
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml


RNA Interference (RNAi) is a system in living cells that helps control the level of activity of genes. In RNAi, a long double stranded RNA is cleaved into shorter strands. One strand known as the guide strand is complimentary to the mRNA gene product of a gene of interest. This guide strand is incorporated into an RNA-induced silencing complex (RISC) and subsequently binds the mRNA of the gene of interest. After binding, the RNA/RISC complex subsequently silences the mRNA of interest via cleavage of the mRNA strand.

PDB ID 1rpu

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viral silencing suppressor bound to a siRNA (1rpu), resolution 2.50Å ()
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml


Articles in Proteopedia concerning RNA Interference include:


To view automatically seeded indices concerning RNA Interference See:


To view other Proteopedia pages about diseases & drug targets, See: Pharmaceutical Drug Targets

Proteopedia Page Contributors and Editors (what is this?)

David Canner, Wayne Decatur, Eric Martz

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