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B-RAF with PLX4032
From Proteopedia
(Difference between revisions)
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<scene name='B-RAF_with_PLX4032/Plx_4032_only/1'>PLX 4032</scene><br> | <scene name='B-RAF_with_PLX4032/Plx_4032_only/1'>PLX 4032</scene><br> | ||
| - | <scene name='B-RAF_with_PLX4032/Wild-type_b-raf/1'> | + | <scene name='B-RAF_with_PLX4032/Wild-type_b-raf/1'>Wild-Type B-RAF</scene> <br> |
| - | + | <scene name='B-RAF_with_PLX4032/Mutated_v600e/1'>V600E Mutation</scene> <br> | |
| - | <scene name='B-RAF_with_PLX4032/ | + | |
<scene name='B-RAF_with_PLX4032/Plx4032_n/1'>PLX4032 Sulfonamide N</scene> <br> | <scene name='B-RAF_with_PLX4032/Plx4032_n/1'>PLX4032 Sulfonamide N</scene> <br> | ||
<scene name='B-RAF_with_PLX4032/Dfg_in_conformation/1'>DFG in</scene><br> | <scene name='B-RAF_with_PLX4032/Dfg_in_conformation/1'>DFG in</scene><br> | ||
Revision as of 01:50, 29 September 2010
B-RAF with PLX4032
PLX4032 is a newly synthesized drug that is being used to treat malignant melanonma with a specific mutation. The mutation is B-RAF^(V600E). This drug is highly selective for this mutation and will not bind to wild type B-RAF.
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