Complexes
From Proteopedia
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Many [[PDB file|PDB files]] contain [[Complexes|complexes]] in which a biological molecule is interacting with another biological molecule in a [[Complexes|complex]] or [[Complexes|assembly]]. These interactions, if biologically relevant, can be immensely insightful in shedding light on cellular and extracellular processes. | Many [[PDB file|PDB files]] contain [[Complexes|complexes]] in which a biological molecule is interacting with another biological molecule in a [[Complexes|complex]] or [[Complexes|assembly]]. These interactions, if biologically relevant, can be immensely insightful in shedding light on cellular and extracellular processes. | ||
| - | |||
| - | ==See Also== | ||
| - | * [[Crystal contacts]] | ||
| - | * [[X-ray crystallography]] | ||
| - | * [[Biological assembly]] | ||
| - | * [[Multi-protein assemblies]] | ||
| - | * [[Ligand]] | ||
==Examples== | ==Examples== | ||
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| - | == | + | ==See Also== |
| - | *[ | + | * [[Multi-protein assemblies]] |
| + | * [[Biological assembly]] | ||
| + | * [[Crystal contacts]] | ||
| + | * [[X-ray crystallography]] | ||
| + | * [[Ligand]] | ||
| - | ==Literature Citations== | ||
| - | Literature citations | + | |
| + | ==External Resources== | ||
| + | * [http://www-cryst.bioc.cam.ac.uk/~richard/piccolo/about.php PICCOLO, a comprehensive relational database featuring the details of structurally characterized protein-protein interactions]. | ||
| + | * [http://pir.georgetown.edu/pro/ PRO] provides an ontological representation of proteins in complexes. In particular, the authors are working to implement logical and consistent representation of protein complexes. | ||
| + | *[https://www.molnac.unisa.it/BioTools/cocomaps/ COCOMAPS (bioCOmplexes COntact MAPS)] is a web server for analysis and visualization of the interfaces present in biological complexes, such as protein-protein, protein-DNA and protein-RNA complexes, making use of intermolecular contact maps. | ||
| + | * [http://haddock.chem.uu.nl/ The HADDOCK web server] is web server for data-driven biomolecular docking for modeling of biomolecular complexes. | ||
| + | |||
| + | ==Literature Citations== | ||
| + | Literature citations can be found at the respective servers linked above. | ||
Current revision
Multi-protein assemblies
Many PDB files contain complexes in which a biological molecule is interacting with another biological molecule in a complex or assembly. These interactions, if biologically relevant, can be immensely insightful in shedding light on cellular and extracellular processes.
Contents |
Examples
- Ribosome
- T7 RNA Polymerase
- Mouse Toll-like receptor bound to dsRNA
- Human Follicle-Stimulating Hormone Complexed with its Receptor
- Platelet-receptor glycoprotein Ib alpha bound to the von Willebrand Factor A1 Domain
- Plant Viral Protein p19 Suppression of RNA Silencing
- RecG Bound to Three-Way DNA Junction
See Also
External Resources
- PICCOLO, a comprehensive relational database featuring the details of structurally characterized protein-protein interactions.
- PRO provides an ontological representation of proteins in complexes. In particular, the authors are working to implement logical and consistent representation of protein complexes.
- COCOMAPS (bioCOmplexes COntact MAPS) is a web server for analysis and visualization of the interfaces present in biological complexes, such as protein-protein, protein-DNA and protein-RNA complexes, making use of intermolecular contact maps.
- The HADDOCK web server is web server for data-driven biomolecular docking for modeling of biomolecular complexes.
Literature Citations
Literature citations can be found at the respective servers linked above.
