1pd8
From Proteopedia
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{{STRUCTURE_1pd8| PDB=1pd8 | SCENE= }} | {{STRUCTURE_1pd8| PDB=1pd8 | SCENE= }} | ||
===Analysis of Three Crystal Structure Determinations of a 5-Methyl-6-N-Methylanilino Pyridopyrimidine Antifolate Complex with Human Dihydrofolate Reductase=== | ===Analysis of Three Crystal Structure Determinations of a 5-Methyl-6-N-Methylanilino Pyridopyrimidine Antifolate Complex with Human Dihydrofolate Reductase=== | ||
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{{ABSTRACT_PUBMED_12925791}} | {{ABSTRACT_PUBMED_12925791}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Anemia, megaloblastic, due to DHFR deficiency (1) OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=126060 126060]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1pd8]] is a 1 chain structure of [[Dihydrofolate reductase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PD8 OCA]. | |
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| + | ==See Also== | ||
| + | *[[Dihydrofolate reductase|Dihydrofolate reductase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:012925791</ref><references group="xtra"/> |
[[Category: Dihydrofolate reductase]] | [[Category: Dihydrofolate reductase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Pangborn, W.]] | [[Category: Pangborn, W.]] | ||
[[Category: Human dihydrofolate reductase inhibitor complex]] | [[Category: Human dihydrofolate reductase inhibitor complex]] | ||
| - | + | [[Category: Oxidoreductase]] | |
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Revision as of 06:09, 26 July 2012
Contents |
Analysis of Three Crystal Structure Determinations of a 5-Methyl-6-N-Methylanilino Pyridopyrimidine Antifolate Complex with Human Dihydrofolate Reductase
Template:ABSTRACT PUBMED 12925791
About this Structure
1pd8 is a 1 chain structure of Dihydrofolate reductase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Cody V, Luft JR, Pangborn W, Gangjee A. Analysis of three crystal structure determinations of a 5-methyl-6-N-methylanilino pyridopyrimidine antifolate complex with human dihydrofolate reductase. Acta Crystallogr D Biol Crystallogr. 2003 Sep;59(Pt 9):1603-9. Epub 2003, Aug 19. PMID:12925791
