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3jwm

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[[Image:3jwm.png|left|200px]]
[[Image:3jwm.png|left|200px]]
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{{STRUCTURE_3jwm| PDB=3jwm | SCENE= }}
{{STRUCTURE_3jwm| PDB=3jwm | SCENE= }}
===Crystal structure of Bacillus anthracis dihydrofolate reductase complexed with NADPH and (S)-2,4-diamino-5-(3-methoxy-3-(3,4,5-trimethoxyphenyl)prop-1-ynyl)-6-methylpyrimidine (UCP114A)===
===Crystal structure of Bacillus anthracis dihydrofolate reductase complexed with NADPH and (S)-2,4-diamino-5-(3-methoxy-3-(3,4,5-trimethoxyphenyl)prop-1-ynyl)-6-methylpyrimidine (UCP114A)===
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{{ABSTRACT_PUBMED_020882962}}
==About this Structure==
==About this Structure==
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==See Also==
==See Also==
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*[[Dihydrofolate reductase]]
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*[[Dihydrofolate reductase|Dihydrofolate reductase]]
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==Reference==
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<ref group="xtra">PMID:020882962</ref><references group="xtra"/>
[[Category: Bacillus anthracis]]
[[Category: Bacillus anthracis]]
[[Category: Dihydrofolate reductase]]
[[Category: Dihydrofolate reductase]]

Revision as of 08:34, 27 July 2012

Template:STRUCTURE 3jwm

Contents

Crystal structure of Bacillus anthracis dihydrofolate reductase complexed with NADPH and (S)-2,4-diamino-5-(3-methoxy-3-(3,4,5-trimethoxyphenyl)prop-1-ynyl)-6-methylpyrimidine (UCP114A)

Template:ABSTRACT PUBMED 020882962

About this Structure

3jwm is a 2 chain structure of Dihydrofolate reductase with sequence from Bacillus anthracis. Full crystallographic information is available from OCA.

See Also

Reference

  • Beierlein JM, Karri NG, Anderson AC. Targeted mutations of Bacillus anthracis dihydrofolate reductase condense complex structure-activity relationships. J Med Chem. 2010 Oct 28;53(20):7327-36. PMID:20882962 doi:10.1021/jm100727t

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