Enolase multiple sequence alignment
From Proteopedia
| Line 4: | Line 4: | ||
Consensus Percentage is set to 100%. | Consensus Percentage is set to 100%. | ||
| - | + | ||
1 ENO_DROME| Drosophila melanogaster <b>G</b>vh<b>EA</b>L<b>E</b>l<b>RD</b> | 1 ENO_DROME| Drosophila melanogaster <b>G</b>vh<b>EA</b>L<b>E</b>l<b>RD</b> | ||
nD<b>K</b>anYh<b>GK</b>S <b>V</b>lk<b>AV</b>ghV<b>N</b>d tLgpelIkan ldvvd<b>Q</b>asI<b>D</b> | nD<b>K</b>anYh<b>GK</b>S <b>V</b>lk<b>AV</b>ghV<b>N</b>d tLgpelIkan ldvvd<b>Q</b>asI<b>D</b> | ||
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<span style="mso-spacerun: | <span style="mso-spacerun: | ||
yes"> | yes"> | ||
| - | </span> | + | </span>01:31, 1 October 2012 (IST)01:31, 1 October 2012 (IST)01:31, 1 October 2012 (IST)01:31, 1 October 2012 (IST)~<br> |
1 ENO_DROME| Drosophila melanogaster gkIeiGm<b>D</b>v<b>A</b> | 1 ENO_DROME| Drosophila melanogaster gkIeiGm<b>D</b>v<b>A</b> | ||
A<b>SEF</b>Yk--d<b>G</b> q<b>Y</b>dLdfknek sdksqwlpad klanlykefi 285<br> | A<b>SEF</b>Yk--d<b>G</b> q<b>Y</b>dLdfknek sdksqwlpad klanlykefi 285<br> | ||
| Line 171: | Line 171: | ||
<span style="mso-spacerun: | <span style="mso-spacerun: | ||
yes"> | yes"> | ||
| - | </span> | + | </span>01:31, 1 October 2012 (IST)01:31, 1 October 2012 (IST)01:31, 1 October 2012 (IST)01:31, 1 October 2012 (IST)~<br> |
1 ENO_DROME| Drosophila melanogaster kdF<b>P</b>IV<b>SIED</b> | 1 ENO_DROME| Drosophila melanogaster kdF<b>P</b>IV<b>SIED</b> | ||
pfdqdhWeAw snltgctd-- I<b>Q</b>I<b>V</b>G<b>DDL</b>t<b>V</b> <b>TN</b>pkrIatAV | pfdqdhWeAw snltgctd-- I<b>Q</b>I<b>V</b>G<b>DDL</b>t<b>V</b> <b>TN</b>pkrIatAV | ||
| Line 189: | Line 189: | ||
6 4ENL Yeast| Saccharomyces cerevisiae krY<b>P</b>IV<b>SIED</b> | 6 4ENL Yeast| Saccharomyces cerevisiae krY<b>P</b>IV<b>SIED</b> | ||
pfaeddWeAw shffktag-- I<b>Q</b>I<b>V</b>A<b>DDL</b>t<b>V</b> <b>TN</b>pkrIatAI | pfaeddWeAw shffktag-- I<b>Q</b>I<b>V</b>A<b>DDL</b>t<b>V</b> <b>TN</b>pkrIatAI | ||
| - | 334 | + | 334 |
Summary of categories applied to a total of 436 residues in the PDB file sequence for a consensus level setting of 100%: | Summary of categories applied to a total of 436 residues in the PDB file sequence for a consensus level setting of 100%: | ||
Revision as of 23:31, 30 September 2012
Multiple Sequence Alignment (MSA) for enolase, an enzyme in glycolysis.
Key: IDENTICAL(*) SIMILAR(.) different Consensus Percentage is set to 100%.
1 ENO_DROME| Drosophila melanogaster GvhEALElRD
nDKanYhGKS VlkAVghVNd tLgpelIkan ldvvdQasID
91
2 ENOA_HUMAN|
Homo sapiens GiyEALElRD nDKtrYmGKG
VskAVehINk tIapalVskk lnvteQekID 90
3 ENO_METJA| Methanococcus janaschii GthEALElRD
kEK-rFgGKG VlmAVenVNs iIrpeiLg-- ydarmQreID
97
4 ENO_ECOLI|
Escherichia coli GsrEALElRD gDKsrFlGKG
VtkAVaaVNg pIaqalIg-- kdakdQagID 90
5 ENO_BACSU| Bacillus
subtilis GeyEAVElRD gDKdrYlGKG VltAVnnVNe
iIapelLg-- fdvteQnaID 91
6 4ENL Yeast| Saccharomyces cerevisiae GvhEALEmRD
gDKskWmGKG VlhAVknVNd vIapafVkan idvsdQkaVD
90<o:p></o:p></span></p>
* **.* ** .* . **. * ** .* . . * .*
1 ENO_DROME| Drosophila melanogaster nfmIklDGTe
NKSKfGANAI LGVSlAvaKA GAakkgvPLY
khIAdlagn- 140
2 ENOA_HUMAN|
Homo sapiens klmIemDGTe NKSKfGANAI LGVSlAvcKA
GAvekgvPLY rhIAdlagn- 139
3 ENO_METJA| Methanococcus janaschii timIelDGTp
NKSRlGANAI LAVSlAvaKA AAatakiPLY
kyLGgfn--- 144
4 ENO_ECOLI|
Escherichia coli kimIdlDGTe NKSKfGANAI LAVSlAnaKA
AAaakgmPLY ehIAelngt- 139
5 ENO_BACSU|
Bacillus subtilis qllIelDGTe NKGKlGANAI LGVSmAcaRA
AAdflqiPLY qyLGgfn--- 138
6 4ENL Yeast| Saccharomyces cerevisiae dflIslDGTa
NKSKlGANAI LGVSlAasRA AAaeknvPLY
khLAdlsksk 140<o:p></o:p>
* *** **.. ***** *.** * .* .* *** .
1 ENO_DROME| Drosophila melanogaster -keiilPVPa
fNVINGGsHA gnkLamQEFM IlPtGAtsft
EAmKmGSeVY 189
2 ENOA_HUMAN|
Homo sapiens -sevilPVPa fNVINGGsHA gnkLamQEFM
IlPvGAanfr EAmRiGAeVY 188
3 ENO_METJA| Methanococcus janaschii --syvmPVPm
mNVINGGkHA gndLdlQEFM ImPvGAtsis
EAvRmGSeVY 192
4 ENO_ECOLI|
Escherichia coli pgkysmPVPm mNIINGGeHA dnnVdiQEFM
IqPvGAktvk EAiRmGSeVF 189
5 ENO_BACSU|
Bacillus subtilis --sktlPVPm mNIVNGGeHA
dnnVdiQEFM ImPvGApnfr EAlRmGAqIF 186
6 4ENL Yeast| Saccharomyces cerevisiae tspyvlPVPf
lNVLNGGsHA ggaLalQEFM IaPtGAktfa
EAlRiGSeVY 190<o:p></o:p>
*** *..*** ** . **** * * ** ** . *. ..<o:p></o:p>
1 ENO_DROME|
Drosophila melanogaster HhLknVikaK fgldataVGD EGGfAPnIqs
nkEALnlIsd AIakAGyt-- 237
2 ENOA_HUMAN|
Homo sapiens HnLknVikeK ygkdatnVGD EGGfAPnIle
nkEGLelLkt AIgkAGyt-- 236
3 ENO_METJA| Methanococcus janaschii HvLknVileK
ygknavnVGD EGGfAPpLkt srEALdlLte SVkkAGye--
240
4 ENO_ECOLI|
Escherichia coli HhLakVlkaK g--mntaVGD EGGyAPnLgs
naEALavIae AVkaAGyelg 237
5 ENO_BACSU|
Bacillus subtilis HsLksVlsaK g--lntaVGD EGGfAPnLgs
neEALqtIve AIekAGfkpg 234
6 4ENL Yeast| Saccharomyces cerevisiae HnLksLtkkR
ygasagnVGD EGGvAPnIqt aeEALdlIvd AIkaAGhd—238<o:p></o:p>
<![if !vml]><img width=155 height=106
src="msa3d_4enl_msa_files/image001.gif" v:shapes="_x0000_s1027"><![endif]>
*
5 ENO_BACSU|
Bacillus subtilis eeVklAmDaA SSEFYnkedG kYhLsgeg--
6 4ENL Yeast| Saccharomyces cerevisiae gkVkiGlDcA
01:31, 1 October 2012 (IST)01:31, 1 October 2012 (IST)01:31, 1 October 2012 (IST)01:31, 1 October 2012 (IST)~
1 ENO_DROME| Drosophila melanogaster gkIeiGmDvA
ASEFYk--dG qYdLdfknek sdksqwlpad klanlykefi 285
2 ENOA_HUMAN|
Homo sapiens dkVviGmDvA ASEFFr--sG kYdLdfksp-
ddpsryispd qladlyksfi 283
3 ENO_METJA| Methanococcus janaschii deVvfAlDaA
ASEFYk--dG yYyVegkk-- ------ltre elldyykalv 280
4 ENO_ECOLI|
Escherichia coli kdItlAmDcA ASEFYk--dG kYvLagegn-
kaftse efthfleelt 280
vvktsa emvdwyeelv 278
. . * * .***. * *
.
01:31, 1 October 2012 (IST)01:31, 1 October 2012 (IST)01:31, 1 October 2012 (IST)01:31, 1 October 2012 (IST)~
1 ENO_DROME| Drosophila melanogaster kdFPIVSIED
pfdqdhWeAw snltgctd-- IQIVGDDLtV TNpkrIatAV
333
2 ENOA_HUMAN|
Homo sapiens kdYPVVSIED pfdqddWgAw qkftasag-- IQVVGDDLtV
TNpkrIakAV 331
3 ENO_METJA| Methanococcus janaschii deYPIVSIED
pfheedFeGf amitkeld-- IQIVGDDLfV TNverLrkGI
328
4 ENO_ECOLI|
Escherichia coli kqYPIVSIED gldesdWdGf ayqtkvlgdk IQLVGDDLfV
TNtkiLkeGI 330
5 ENO_BACSU|
Bacillus subtilis skYPIISIED gldendWeGh kllterlgkk VQLVGDDLfV
TNtkkLseGI 328
6 4ENL Yeast| Saccharomyces cerevisiae krYPIVSIED
pfaeddWeAw shffktag-- IQIVADDLtV TNpkrIatAI
334
Summary of categories applied to a total of 436 residues in the PDB file sequence for a consensus level setting of 100%:
33% (142) IDENTICAL(*) 16% (68) SIMILAR(.) 52% (226) different
Definitions of SIMILAR groups of amino acids:
ILV Ile Leu Val hydrophobic, aliphatic / medium-sized side-chain
FWY Phe Trp Tyr hydrophobic, aromatic / large side-chain (Tyr polar)
KRH Lys Arg His + charge
DE Asp Glu - charge
GAS Gly Ala Ser small
P Pro helix breaking
C Cys disulfide-forming
TNQM Thr Asn Gln Met polar (except Met)
