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Enolase multiple sequence alignment

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Revision as of 23:53, 30 September 2012

Multiple Sequence Alignment (MSA) for enolase, an enzyme in glycolysis.

Key: IDENTICAL(*) SIMILAR(.) different Consensus Percentage is set to 100%.

1    ENO_DROME| Drosophila melanogaster --------mt IkaIkARqIy DSRGNPTVEv DLtt-elglf rAavPSGAST 41
2              ENOA_HUMAN| Homo sapiens ---------s IlkIhAReIf DSRGNPTVEv DLft-skglf rAavPSGAST 40
3    ENO_METJA| Methanococcus janaschii mlynmderfe IkdIvAReVi DSRGNPTVEv EVitkgngyg sAivPSGAST 50
4           ENO_ECOLI| Escherichia coli --------sk IvkIiGReIi DSRGNPTVEa EVhleggfvg mAaaPSGAST 42
5          ENO_BACSU| Bacillus subtilis -------mpy IvdVyAReVl DSRGNPTVEv EVytetgafg rAlvPSGAST 43
6  4ENL Yeast| Saccharomyces cerevisiae ---------a VskVyARsVy DSRGNPTVEv ELtt-ekgvf rSivPSGAST 40

                                                     . . .* . ********* ..          . ******

1    ENO_DROME| Drosophila melanogaster GvhEALElRD nDKanYhGKS VlkAVghVNd tLgpelIkan ldvvdQasID 91
2              ENOA_HUMAN| Homo sapiens GiyEALElRD nDKtrYmGKG VskAVehINk tIapalVskk lnvteQekID 90
3    ENO_METJA| Methanococcus janaschii GthEALElRD kEK-rFgGKG VlmAVenVNs iIrpeiLg-- ydarmQreID 97
4           ENO_ECOLI| Escherichia coli GsrEALElRD gDKsrFlGKG VtkAVaaVNg pIaqalIg-- kdakdQagID 90
5          ENO_BACSU| Bacillus subtilis GeyEAVElRD gDKdrYlGKG VltAVnnVNe iIapelLg-- fdvteQnaID 91
6  4ENL Yeast| Saccharomyces cerevisiae GvhEALEmRD gDKskWmGKG VlhAVknVNd vIapafVkan idvsdQkaVD 90

                                          * **.* ** .* . **. * ** .*   .   .         * .*

1    ENO_DROME| Drosophila melanogaster nfmIklDGTe NKSKfGANAI LGVSlAvaKA GAakkgvPLY khIAdlagn- 140
2              ENOA_HUMAN| Homo sapiens klmIemDGTe NKSKfGANAI LGVSlAvcKA GAvekgvPLY rhIAdlagn- 139
3    ENO_METJA| Methanococcus janaschii timIelDGTp NKSRlGANAI LAVSlAvaKA AAatakiPLY kyLGgfn--- 144
4           ENO_ECOLI| Escherichia coli kimIdlDGTe NKSKfGANAI LAVSlAnaKA AAaakgmPLY ehIAelngt- 139
5          ENO_BACSU| Bacillus subtilis qllIelDGTe NKGKlGANAI LGVSmAcaRA AAdflqiPLY qyLGgfn--- 138
6  4ENL Yeast| Saccharomyces cerevisiae dflIslDGTa NKSKlGANAI LGVSlAasRA AAaeknvPLY khLAdlsksk 140

                                             * *** **.. ***** *.** * .* .*     ***    .

1    ENO_DROME| Drosophila melanogaster -keiilPVPa fNVINGGsHA gnkLamQEFM IlPtGAtsft EAmKmGSeVY 189
2              ENOA_HUMAN| Homo sapiens -sevilPVPa fNVINGGsHA gnkLamQEFM IlPvGAanfr EAmRiGAeVY 188
3    ENO_METJA| Methanococcus janaschii --syvmPVPm mNVINGGkHA gndLdlQEFM ImPvGAtsis EAvRmGSeVY 192
4           ENO_ECOLI| Escherichia coli pgkysmPVPm mNIINGGeHA dnnVdiQEFM IqPvGAktvk EAiRmGSeVF 189
5          ENO_BACSU| Bacillus subtilis --sktlPVPm mNIVNGGeHA dnnVdiQEFM ImPvGApnfr EAlRmGAqIF 186
6  4ENL Yeast| Saccharomyces cerevisiae tspyvlPVPf lNVLNGGsHA ggaLalQEFM IaPtGAktfa EAlRiGSeVY 190

*** *..*** ** . **** * * ** ** . *. ..

1    ENO_DROME| Drosophila melanogaster HhLknVikaK fgldataVGD EGGfAPnIqs nkEALnlIsd AIakAGyt-- 237
2              ENOA_HUMAN| Homo sapiens HnLknVikeK ygkdatnVGD EGGfAPnIle nkEGLelLkt AIgkAGyt-- 236
3    ENO_METJA| Methanococcus janaschii HvLknVileK ygknavnVGD EGGfAPpLkt srEALdlLte SVkkAGye-- 240
4           ENO_ECOLI| Escherichia coli HhLakVlkaK g--mntaVGD EGGyAPnLgs naEALavIae AVkaAGyelg 237
5          ENO_BACSU| Bacillus subtilis HsLksVlsaK g--lntaVGD EGGfAPnLgs neEALqtIve AIekAGfkpg 234
6  4ENL Yeast| Saccharomyces cerevisiae HnLksLtkkR ygasagnVGD EGGvAPnIqt aeEALdlIvd AIkaAG-- 238

                                          ** .   .        *** *** ** .     *.* .   .. **

1    ENO_DROME| Drosophila melanogaster gkIeiGmDvA ASEFYk--dG qYdLdfknek sdksqwlpad klanlykefi 285
2              ENOA_HUMAN| Homo sapiens dkVviGmDvA ASEFFr--sG kYdLdfksp- ddpsryispd qladlyksfi 283
3    ENO_METJA| Methanococcus janaschii deVvfAlDaA ASEFYk--dG yYyVegkk-- ------ltre elldyykalv 280
4           ENO_ECOLI| Escherichia coli kdItlAmDcA ASEFYk--dG kYvLagegn- ----kaftse efthfleelt 280
5          ENO_BACSU| Bacillus subtilis eeVklAmDaA SSEFYnkedG kYhLsgeg-- ----vvktsa emvdwyeelv 278
6  4ENL Yeast| Saccharomyces cerevisiae gkVkiGlDcA SSEFFk--dG kYdLdfknpn sdkskwltgp qladlyhslm 286

                                            . . * * .***.    * * .

1    ENO_DROME| Drosophila melanogaster kdFPIVSIED pfdqdhWeAw snltgctd-- IQIVGDDLtV TNpkrIatAV 333
2              ENOA_HUMAN| Homo sapiens kdYPVVSIED pfdqddWgAw qkftasag-- IQVVGDDLtV TNpkrIakAV 331
3    ENO_METJA| Methanococcus janaschii deYPIVSIED pfheedFeGf amitkeld-- IQIVGDDLfV TNverLrkGI 328
4           ENO_ECOLI| Escherichia coli kqYPIVSIED gldesdWdGf ayqtkvlgdk IQLVGDDLfV TNtkiLkeGI 330
5          ENO_BACSU| Bacillus subtilis skYPIISIED gldendWeGh kllterlgkk VQLVGDDLfV TNtkkLseGI 328
6  4ENL Yeast| Saccharomyces cerevisiae krYPIVSIED pfaeddWeAw shffktag-- IQIVADDLtV TNpkrIatAI 334

                                            .*..****       . .             .*.*.*** * **   . ..

1    ENO_DROME| Drosophila melanogaster ekkacncLLL KvNQIGtVtE siaAhllAkk nGWgtmVSHR SGETEDsfIG 383
2              ENOA_HUMAN| Homo sapiens nekscncLLL KvNQIGsVtE slqAcklAqa nGWgvmVSHR SGETEDtfIA 381
3    ENO_METJA| Methanococcus janaschii emkaanaLLL KvNQIGtLsE avdAaqlAfr nGYgvvVSHR SGETEDttIA 378
4           ENO_ECOLI| Escherichia coli ekgiansILI KfNQIGsLtE tlaAikmAkd aGYtavISHR SGETEDatIA 380
5          ENO_BACSU| Bacillus subtilis kngvgnsILI KvNQIGtLtE tfdAiemAkr aGYtavISHR SGETEDstIA 378
6  4ENL Yeast| Saccharomyces cerevisiae ekkaadaLLL KvNQIGtLsE sikAaqdSfa aGWgvmVSHR SGETEDtfIA 384

                                                 .*. . **** . *    *   .    *.   .*** ****** *.

1    ENO_DROME| Drosophila melanogaster DLvVGlstGQ IKTGApcRsE RlAKyNQILR IEeeIGagvk FaGksfgkpq 433
2              ENOA_HUMAN| Homo sapiens DLvVGlctGQ IKTGApcRsE RlAKyNQLLR IEeeLGskak FaGrnfrnpl 431
3    ENO_METJA| Methanococcus janaschii DLsVAlnsGQ IKTGApaRgE RtAKyNQLIR IEqeLG-lsk YaGrnfrcpf 427
4           ENO_ECOLI| Escherichia coli DLaVGtaaGQ IKTGSmsRsD RvAKyNQLIR IEeaLGekap YnGrkeikgq 430
5          ENO_BACSU| Bacillus subtilis DIaVAtnaGQ IKTGApsRtD RvAKyNQLLR IEdqLAetaq YhGinsfynl 428
6  4ENL Yeast| Saccharomyces cerevisiae DLvVGlrtGQ IKTGApaRsE RlAKlNQLLR IEeeLGdnav FaGenfhhgd 434

*. *. ** ****. * . * ** **..* ** .. . *

Summary of categories applied to a total of 436 residues in the PDB file sequence for a consensus level setting of 100%:

33% (142) IDENTICAL(*) 16% (68) SIMILAR(.) 52% (226) different

Definitions of SIMILAR groups of amino acids:

ILV       Ile Leu Val          hydrophobic, aliphatic / medium-sized side-chain
FWY     Phe Trp Tyr         hydrophobic, aromatic / large side-chain (Tyr polar)
KRH     Lys Arg His         + charge
DE        Asp Glu                - charge
GAS     Gly Ala Ser           small
P           Pro                        helix breaking
C           Cys                       disulfide-forming
TNQM  Thr Asn Gln Met  polar (except Met)

Proteopedia Page Contributors and Editors (what is this?)

Eric Martz

Retrieved from "http://52.214.119.220/wiki/index.php/Enolase_multiple_sequence_alignment"

@@ Line 22: / Line 22: @@
 EVytetgafg rAlv<b>PSGAST</b> 43<br>
 &nbsp;6&nbsp;&nbsp;4ENL Yeast| Saccharomyces cerevisiae &nbsp;---------a VskVyA<b>R</b>sVy
-<b>DSRGNPTVE</b>v ELtt-ekgvf rSiv<b>PSGAST</b> 40<o:p></o:p></span></p>
+<b>DSRGNPTVE</b>v ELtt-ekgvf rSiv<b>PSGAST</b> 40</span></p>
 <p class=MsoNormal><span style='font-size:10.0pt;font-family:"Courier New";
@@ Line 51: / Line 51: @@
 &nbsp;6&nbsp;&nbsp;4ENL Yeast| Saccharomyces cerevisiae &nbsp;<b>G</b>vh<b>EA</b>L<b>E</b>m<b>RD</b>
 gD<b>K</b>skWm<b>GK</b>G <b>V</b>lh<b>AV</b>knV<b>N</b>d vIapafVkan idvsd<b>Q</b>kaV<b>D</b>
-<o:p></o:p></span></p>
+</span></p>
 <p class=MsoNormal><span style='font-size:10.0pt;font-family:"Courier New";
@@ Line 82: / Line 82: @@
 &nbsp;6&nbsp;&nbsp;4ENL Yeast| Saccharomyces cerevisiae &nbsp;dfl<b>I</b>sl<b>DGT</b>a
 <b>NK</b>SKl<b>GANAI</b> <b>L</b>G<b>VS</b>l<b>A</b>asR<b>A</b> A<b>A</b>aeknv<b>PLY</b>
-khLAdlsksk 140<o:p></o:p></span></p>
+khLAdlsksk 140</span></p>
 <p class=MsoNormal><span style='font-size:10.0pt;font-family:"Courier New";
@@ Line 110: / Line 110: @@
 &nbsp;6&nbsp;&nbsp;4ENL Yeast| Saccharomyces cerevisiae &nbsp;tspyvl<b>PVP</b>f
 l<b>N</b>VL<b>NGG</b>s<b>HA</b> ggaLal<b>QEFM</b> <b>I</b>a<b>P</b>t<b>GA</b>ktfa
-<b>EA</b>lRi<b>G</b>SeVY 190<o:p></o:p></span></p>
+<b>EA</b>lRi<b>G</b>SeVY 190</span></p>
 <p class=MsoNormal><span style='font-size:10.0pt;font-family:"Courier New";
@@ Line 118: / Line 118: @@
 style="mso-spacerun: yes">&nbsp;&nbsp;&nbsp; </span>.<span style="mso-spacerun:
 yes">&nbsp; </span>**** * * **<span style="mso-spacerun:
-yes">&nbsp;&nbsp;&nbsp;&nbsp; </span>** . *. ..<o:p></o:p></span></p>
+yes">&nbsp;&nbsp;&nbsp;&nbsp; </span>** . *. ..</span></p>
 <span style='font-size:10.0pt;font-family:"Courier New";mso-fareast-font-family:
@@ Line 174: / Line 174: @@
  ----vvktsa emvdwyeelv 278<br>
 &nbsp;6&nbsp;&nbsp;4ENL Yeast| Saccharomyces cerevisiae &nbsp;gkVkiGl<b>D</b>c<b>A</b>
-S<b>SEF</b>Fk--d<b>G</b> k<b>Y</b>dLdfknpn sdkskwltgp qladlyhslm 286<o:p></o:p></span></p>
+S<b>SEF</b>Fk--d<b>G</b> k<b>Y</b>dLdfknpn sdkskwltgp qladlyhslm 286</span></p>
 <p class=MsoNormal><span style='font-size:10.0pt;font-family:"Courier New";
@@ Line 206: / Line 206: @@
 &nbsp;6&nbsp;&nbsp;4ENL Yeast| Saccharomyces cerevisiae &nbsp;krY<b>P</b>IV<b>SIED</b>
 pfaeddWeAw shffktag-- I<b>Q</b>I<b>V</b>A<b>DDL</b>t<b>V</b> <b>TN</b>pkrIatAI
-<o:p></o:p></span></p>
+</span></p>
 <p class=MsoNormal><span style='font-size:10.0pt;font-family:"Courier New";
@@ Line 236: / Line 236: @@
 &nbsp;6&nbsp;&nbsp;4ENL Yeast| Saccharomyces cerevisiae &nbsp;ekkaadaL<b>L</b>L
 <b>K</b>v<b>NQIG</b>tLs<b>E</b> sik<b>A</b>aqdSfa a<b>G</b>WgvmV<b>SHR</b> <b>SGETED</b>tf<b>I</b>A
-<o:p></o:p></span></p>
+</span></p>
 <p class=MsoNormal><span style='font-size:10.0pt;font-family:"Courier New";
@@ Line 264: / Line 264: @@
 &nbsp;6&nbsp;&nbsp;4ENL Yeast| Saccharomyces cerevisiae &nbsp;<b>D</b>Lv<b>V</b>Glrt<b>GQ</b>
 <b>IKTG</b>Apa<b>R</b>sE <b>R</b>l<b>AK</b>l<b>NQ</b>LL<b>R</b> <b>IE</b>eeLGdnav
-Fa<b>G</b>enfhhgd 434<o:p></o:p></span></p>
+Fa<b>G</b>enfhhgd 434</span></p>
 <p class=MsoNormal><span style='font-size:10.0pt;font-family:"Courier New";
@@ Line 272: / Line 272: @@
 style="mso-spacerun: yes">&nbsp; </span>* . * ** **..* **<span
 style="mso-spacerun: yes">&nbsp; </span>..<span style="mso-spacerun:
-yes">&nbsp;&nbsp;&nbsp;&nbsp; </span>. *<o:p></o:p></span></p>
+yes">&nbsp;&nbsp;&nbsp;&nbsp; </span>. *</span></p>
 <span style='font-size:10.0pt;font-family:"Courier New";mso-fareast-font-family:
@@ Line 292: / Line 292: @@
 </span></p>
+Summary of categories applied to a total of 436 residues in the PDB file sequence for a consensus level setting of 100%:
+% (142) IDENTICAL(*)   16% (68) SIMILAR(.)   52% (226) different
+Definitions of SIMILAR groups of amino acids:<pre>
-Summary of categories applied to a total of 436 residues in the PDB file sequence for a consensus level setting of 100%:
-% (142) IDENTICAL(*)   16% (68) SIMILAR(.)   52% (226) different
-Definitions of SIMILAR groups of amino acids:
 ILV       Ile Leu Val          hydrophobic, aliphatic / medium-sized side-chain
 FWY     Phe Trp Tyr         hydrophobic, aromatic / large side-chain (Tyr polar)
@@ Line 306: / Line 305: @@
 C           Cys                       disulfide-forming
 TNQM  Thr Asn Gln Met  polar (except Met)
+</pre>

Enolase multiple sequence alignment

From Proteopedia

Revision as of 23:53, 30 September 2012

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