1qzf
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | [[1qzf]] is a 5 chain structure | + | [[1qzf]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Cryptosporidium_hominis Cryptosporidium hominis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QZF OCA]. |
==See Also== | ==See Also== | ||
Revision as of 12:21, 20 October 2012
Contents |
Crystal structure of DHFR-TS from Cryptosporidium hominis
Template:ABSTRACT PUBMED 14555647
About this Structure
1qzf is a 5 chain structure with sequence from Cryptosporidium hominis. Full crystallographic information is available from OCA.
See Also
Reference
- O'Neil RH, Lilien RH, Donald BR, Stroud RM, Anderson AC. Phylogenetic classification of protozoa based on the structure of the linker domain in the bifunctional enzyme, dihydrofolate reductase-thymidylate synthase. J Biol Chem. 2003 Dec 26;278(52):52980-7. Epub 2003 Oct 9. PMID:14555647 doi:10.1074/jbc.M310328200
- Anderson AC. Two crystal structures of dihydrofolate reductase-thymidylate synthase from Cryptosporidium hominis reveal protein-ligand interactions including a structural basis for observed antifolate resistance. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Mar 1;61(Pt, 3):258-62. Epub 2005 Feb 8. PMID:16511011 doi:10.1107/S1744309105002435
