NF-Y Transcription Factor Sandbox
From Proteopedia
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| - | == Function == | + | == Protein Function == |
| - | == | + | == Protein Structure == |
| - | NF-Y transcription factor has three subunits composed of NF-YA, NF-YB, and NFY-C alpha helices. NF-YA subunit binds to both NF-YB and NF-YC subunits. The C terminal <scene name='56/566534/Lab_minor_groove_and_a2/1'>A2 helix</scene> of the NF-YA subunit inserts deep into the minor groove of DNA while the N terminal A1 helix of the NF-YA subunit interacts with NF-YB and NF-YC subunits. NF-YA A2 helix binds to the <scene name='56/566534/Ccaat_box/4'>CCAAT</scene> box and causes the minor groove to widen at the CCAAT box. An important residue in the catalytic site is <scene name='56/566534/Lysine_138 | + | NF-Y transcription factor has three subunits composed of <scene name='56/566534/Nf-ya_helices/1'>NF-YA</scene>, NF-YB, and NFY-C alpha helices. NF-YA subunit binds to both NF-YB and NF-YC subunits. |
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| + | == Interaction With DNA == | ||
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| + | The C terminal <scene name='56/566534/Lab_minor_groove_and_a2/1'>A2 helix</scene> of the NF-YA subunit inserts deep into the minor groove of DNA while the N terminal A1 helix of the NF-YA subunit interacts with NF-YB and NF-YC subunits. NF-YA A2 helix binds to the <scene name='56/566534/Ccaat_box/4'>CCAAT</scene> box and causes the minor groove to widen at the CCAAT box. An important residue in the catalytic site is <scene name='56/566534/Lysine_138 | ||
<scene name='56/566534/Workkk/1'>kk</scene>. | <scene name='56/566534/Workkk/1'>kk</scene>. | ||
Revision as of 03:11, 5 November 2013
Protein Function
Protein Structure
NF-Y transcription factor has three subunits composed of , NF-YB, and NFY-C alpha helices. NF-YA subunit binds to both NF-YB and NF-YC subunits.
Interaction With DNA
The C terminal of the NF-YA subunit inserts deep into the minor groove of DNA while the N terminal A1 helix of the NF-YA subunit interacts with NF-YB and NF-YC subunits. NF-YA A2 helix binds to the box and causes the minor groove to widen at the CCAAT box. An important residue in the catalytic site is . . . . . . .
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