2fzh

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:2fzh.png|left|200px]]
 
- 
{{STRUCTURE_2fzh| PDB=2fzh | SCENE= }}
{{STRUCTURE_2fzh| PDB=2fzh | SCENE= }}
- 
===New Insights into Dihydrofolate Reductase Interactions: Analysis of Pneumocystis carinii and Mouse DHFR Complexes with NADPH and Two Highly Potent Trimethoprim Derivatives===
===New Insights into Dihydrofolate Reductase Interactions: Analysis of Pneumocystis carinii and Mouse DHFR Complexes with NADPH and Two Highly Potent Trimethoprim Derivatives===
 +
{{ABSTRACT_PUBMED_17019704}}
-
{{ABSTRACT_PUBMED_17019704}}
+
==Function==
 +
[[http://www.uniprot.org/uniprot/DYR_PNECA DYR_PNECA]] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
==About this Structure==
==About this Structure==
-
[[2fzh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pneumocystis_carinii Pneumocystis carinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FZH OCA].
+
[[2fzh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pneca Pneca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FZH OCA].
==See Also==
==See Also==
Line 14: Line 13:
==Reference==
==Reference==
-
<ref group="xtra">PMID:017019704</ref><references group="xtra"/>
+
<ref group="xtra">PMID:017019704</ref><references group="xtra"/><references/>
[[Category: Dihydrofolate reductase]]
[[Category: Dihydrofolate reductase]]
-
[[Category: Pneumocystis carinii]]
+
[[Category: Pneca]]
[[Category: Chisum, K.]]
[[Category: Chisum, K.]]
[[Category: Cody, V.]]
[[Category: Cody, V.]]

Revision as of 12:19, 20 November 2013

Template:STRUCTURE 2fzh

Contents

New Insights into Dihydrofolate Reductase Interactions: Analysis of Pneumocystis carinii and Mouse DHFR Complexes with NADPH and Two Highly Potent Trimethoprim Derivatives

Template:ABSTRACT PUBMED 17019704

Function

[DYR_PNECA] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

About this Structure

2fzh is a 1 chain structure with sequence from Pneca. Full crystallographic information is available from OCA.

See Also

Reference

  • Cody V, Pace J, Chisum K, Rosowsky A. New insights into DHFR interactions: analysis of Pneumocystis carinii and mouse DHFR complexes with NADPH and two highly potent 5-(omega-carboxy(alkyloxy) trimethoprim derivatives reveals conformational correlations with activity and novel parallel ring stacking interactions. Proteins. 2006 Dec 1;65(4):959-69. PMID:17019704 doi:10.1002/prot.21131

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2fzh"
Personal tools