3kc4

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:3kc4.png|left|200px]]
+
==Ribosome-SecY complex. This entry 3KC4 contains 30S ribosomal subnit. The 50S ribosomal subunit can be found in PDB entry 3KCR==
 +
<StructureSection load='3kc4' size='340' side='right' caption='[[3kc4]], [[Resolution|resolution]] 9.60&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[3kc4]] is a 21 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KC4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KC4 FirstGlance]. <br>
 +
</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3bo0|3bo0]], [[3bo1|3bo1]], [[3kcr|3kcr]]</td></tr>
 +
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kc4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kc4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3kc4 RCSB], [http://www.ebi.ac.uk/pdbsum/3kc4 PDBsum]</span></td></tr>
 +
<table>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kc/3kc4_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
 +
<div style="clear:both"></div>
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
During protein synthesis, it is often necessary for the ribosome to form a complex with a membrane-bound channel, the SecY/Sec61 complex, in order to translocate nascent proteins across a cellular membrane. Structural data on the ribosome-channel complex are currently limited to low-resolution cryo-electron microscopy maps, including one showing a bacterial ribosome bound to a monomeric SecY complex. Using that map along with available atomic-level models of the ribosome and SecY, we have determined, through molecular dynamics flexible fitting (MDFF), an atomic-resolution model of the ribosome-channel complex. We characterized computationally the sites of ribosome-SecY interaction within the complex and determined the effect of ribosome binding on the SecY channel. We also constructed a model of a ribosome in complex with a SecY dimer by adding a second copy of SecY to the MDFF-derived model. The study involved 2.7-million-atom simulations over altogether nearly 50 ns.
-
{{STRUCTURE_3kc4| PDB=3kc4 | SCENE= }}
+
Regulation of the protein-conducting channel by a bound ribosome.,Gumbart J, Trabuco LG, Schreiner E, Villa E, Schulten K Structure. 2009 Nov 11;17(11):1453-64. PMID:19913480<ref>PMID:19913480</ref>
-
===Ribosome-SecY complex. This entry 3KC4 contains 30S ribosomal subnit. The 50S ribosomal subunit can be found in PDB entry 3KCR===
+
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-
 
+
</div>
-
{{ABSTRACT_PUBMED_19913480}}
+
-
 
+
-
==About this Structure==
+
-
[[3kc4]] is a 21 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KC4 OCA].
+
==See Also==
==See Also==
-
*[[Ribosomal protein S10|Ribosomal protein S10]]
 
-
*[[Ribosomal protein S11|Ribosomal protein S11]]
 
-
*[[Ribosomal protein S12|Ribosomal protein S12]]
 
-
*[[Ribosomal protein S13|Ribosomal protein S13]]
 
-
*[[Ribosomal protein S14|Ribosomal protein S14]]
 
-
*[[Ribosomal protein S15|Ribosomal protein S15]]
 
-
*[[Ribosomal protein S16|Ribosomal protein S16]]
 
-
*[[Ribosomal protein S17|Ribosomal protein S17]]
 
-
*[[Ribosomal protein S18|Ribosomal protein S18]]
 
-
*[[Ribosomal protein S19|Ribosomal protein S19]]
 
*[[Ribosomal protein S2|Ribosomal protein S2]]
*[[Ribosomal protein S2|Ribosomal protein S2]]
-
*[[Ribosomal protein S20|Ribosomal protein S20]]
 
*[[Ribosomal protein S21|Ribosomal protein S21]]
*[[Ribosomal protein S21|Ribosomal protein S21]]
*[[Ribosomal protein S3|Ribosomal protein S3]]
*[[Ribosomal protein S3|Ribosomal protein S3]]
-
*[[Ribosomal protein S4|Ribosomal protein S4]]
+
*[[Ribosome 3D structures|Ribosome 3D structures]]
-
*[[Ribosomal protein S5|Ribosomal protein S5]]
+
== References ==
-
*[[Ribosomal protein S6|Ribosomal protein S6]]
+
<references/>
-
*[[Ribosomal protein S7|Ribosomal protein S7]]
+
__TOC__
-
*[[Ribosomal protein S8|Ribosomal protein S8]]
+
</StructureSection>
-
*[[Ribosomal protein S9|Ribosomal protein S9]]
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:019913480</ref><references group="xtra"/>
+
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli k-12]]
[[Category: Escherichia coli k-12]]

Revision as of 11:04, 29 September 2014

Ribosome-SecY complex. This entry 3KC4 contains 30S ribosomal subnit. The 50S ribosomal subunit can be found in PDB entry 3KCR

3kc4, resolution 9.60Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3kc4"
Views
Personal tools
Navigation
Toolbox