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3ah3
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ah3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ah3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ah3 RCSB], [http://www.ebi.ac.uk/pdbsum/3ah3 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ah3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ah3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ah3 RCSB], [http://www.ebi.ac.uk/pdbsum/3ah3 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/Q72IW9_THET2 Q72IW9_THET2]] Catalyzes the NAD(+)-dependent conversion of homoisocitrate to alpha-ketoadipate. In addition, has high activity with citrate, but is inactive with 3-isopropylmalate.<ref>PMID:12427751</ref> <ref>PMID:20735360</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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[[Category: Homoisocitrate dehydrogenase]] | [[Category: Homoisocitrate dehydrogenase]] | ||
[[Category: Thermus thermophilus]] | [[Category: Thermus thermophilus]] | ||
| - | [[Category: Kuzuyama, T | + | [[Category: Kuzuyama, T]] |
| - | [[Category: Nishiyama, M | + | [[Category: Nishiyama, M]] |
| - | [[Category: Suzuki, Y | + | [[Category: Suzuki, Y]] |
| - | [[Category: Tomita, T | + | [[Category: Tomita, T]] |
[[Category: 3-isopropylmalate dehydrogenase]] | [[Category: 3-isopropylmalate dehydrogenase]] | ||
[[Category: Directed evolution]] | [[Category: Directed evolution]] | ||
| - | [[Category: Homoisocitrate dehydrogenase]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
Revision as of 10:10, 25 December 2014
Crystal structure of LR5-1, 3-isopropylmalate dehydrogenase created by directed evolution
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