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4u5m
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4u5m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u5m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4u5m RCSB], [http://www.ebi.ac.uk/pdbsum/4u5m PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4u5m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u5m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4u5m RCSB], [http://www.ebi.ac.uk/pdbsum/4u5m PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Aside from the well-known double helix, DNA can also adopt an alternative four-stranded structure known as G-quadruplex. Implications of such a structure in cellular processes, as well as its therapeutic and diagnostic applications, have been reported. The G-quadruplex structure is highly polymorphic, but so far, only right-handed helical forms have been observed. Here we present the NMR solution and X-ray crystal structures of a left-handed DNA G-quadruplex. The structure displays unprecedented features that can be exploited as unique recognition elements. | ||
| + | |||
| + | Structure of a left-handed DNA G-quadruplex.,Chung WJ, Heddi B, Schmitt E, Lim KW, Mechulam Y, Phan AT Proc Natl Acad Sci U S A. 2015 Feb 18. pii: 201418718. PMID:25695967<ref>PMID:25695967</ref> | ||
| + | |||
| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 11:24, 4 March 2015
Structure of a left-handed DNA G-quadruplex
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Categories: Brahim, H | Chung, W J | Lim, K W | Mechulam, Y | Phan, A T | Schmitt, E | Dna | Quadruplex
