Dipeptidyl peptidase
From Proteopedia
(Difference between revisions)
| Line 20: | Line 20: | ||
**[[1jqp]] – rDPP-I – rat<br /> | **[[1jqp]] – rDPP-I – rat<br /> | ||
**[[1k3b]], [[2djg]] - hDPP-I – human<br /> | **[[1k3b]], [[2djg]] - hDPP-I – human<br /> | ||
| - | **[[3pdf]], [[2djf]] – hDPP-I + inhibitor | + | **[[3pdf]], [[2djf]], [[4cdc]], [[4cdd]], [[4cde]], [[4cdf]] – hDPP-I + inhibitor |
*DPP-II | *DPP-II | ||
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**[[1u8e]] – hDPP-IV extracellular domain (mutant)<br /> | **[[1u8e]] – hDPP-IV extracellular domain (mutant)<br /> | ||
**[[3kwj]], [[3oc0]], [[3kwf]], [[3q8w]] – hDPP-IV extracellular domain +quinoline derivative<br /> | **[[3kwj]], [[3oc0]], [[3kwf]], [[3q8w]] – hDPP-IV extracellular domain +quinoline derivative<br /> | ||
| - | **[[3g0b]], [[3g0d]], [[3g0g]], [[3nox]], [[3hab]], [[3hac]], [[3f8s]], [[3h0c]], [[3ccb]], [[3ccc]], [[2qjr]], [[2qky]], [[3d4l]], [[2jid]], [[3bjm]], [[2rip]], [[2ole]], [[2rgu]], [[2i78]], [[2oag]], [[2oqv]], [[2oqi]], [[2ogz]], [[2i03]], [[2g5p]], [[2g5t]], [[2g63]], [[2bub]], [[2ajl]], [[1wcy]], [[1rwq]], [[1tkr]], [[1n1m]], [[3eio]], [[3g0c]], [[3opm]], [[3sww]], [[3sx4]], [[3q0t]], [[4a5s]], [[3vjk]], [[3vjl]], [[3vjm]], [[3w2t]], [[4dsa]], [[4dsz]], [[4dtc]], [[4g1f]],[[3o95]], [[3o9v]], [[4j3j]], [[4jh0]], [[4lko]], [[4n8d]], [[4n8e]] – hDPP-IV extracellular domain+inhibitor<br /> | + | **[[3g0b]], [[3g0d]], [[3g0g]], [[3nox]], [[3hab]], [[3hac]], [[3f8s]], [[3h0c]], [[3ccb]], [[3ccc]], [[2qjr]], [[2qky]], [[3d4l]], [[2jid]], [[3bjm]], [[2rip]], [[2ole]], [[2rgu]], [[2i78]], [[2oag]], [[2oqv]], [[2oqi]], [[2ogz]], [[2i03]], [[2g5p]], [[2g5t]], [[2g63]], [[2bub]], [[2ajl]], [[1wcy]], [[1rwq]], [[1tkr]], [[1n1m]], [[3eio]], [[3g0c]], [[3opm]], [[3sww]], [[3sx4]], [[3q0t]], [[4a5s]], [[3vjk]], [[3vjl]], [[3vjm]], [[3w2t]], [[4dsa]], [[4dsz]], [[4dtc]], [[4g1f]],[[3o95]], [[3o9v]], [[4j3j]], [[4jh0]], [[4lko]], [[4n8d]], [[4n8e]], [[4pnz]], [[4pv7]] – hDPP-IV extracellular domain+inhibitor<br /> |
**[[1r9n]], [[2bgr]], [[1nu8]] – hDPP-IV extracellular domain+polypeptide<br /> | **[[1r9n]], [[2bgr]], [[1nu8]] – hDPP-IV extracellular domain+polypeptide<br /> | ||
**[[1w1i]] – hDPP-IV extracellular domain+adenosine deaminase<br /> | **[[1w1i]] – hDPP-IV extracellular domain+adenosine deaminase<br /> | ||
**[[2bgn]] – hDPP-IV extracellular domain+adenosine deaminase+polypeptide<br /> | **[[2bgn]] – hDPP-IV extracellular domain+adenosine deaminase+polypeptide<br /> | ||
**[[3c43]], [[3c45]], [[2qoe]], [[2qt9]], [[2qtb]], [[2p8s]], [[2oph]], [[2fjp]], [[1x70]], [[2iit]], [[2iiv]], [[3qbj]] – hDPP-IV extracellular domain (mutant) + inhibitor <br /> | **[[3c43]], [[3c45]], [[2qoe]], [[2qt9]], [[2qtb]], [[2p8s]], [[2oph]], [[2fjp]], [[1x70]], [[2iit]], [[2iiv]], [[3qbj]] – hDPP-IV extracellular domain (mutant) + inhibitor <br /> | ||
| - | **[[4kr0]] - hDPP-IV extracellular domain + S protein<br /> | + | **[[4kr0]], [[4qzv]] - hDPP-IV extracellular domain + S protein<br /> |
**[[4l72]] – rDPP-IV + Mers-Cov Rbd<br /> | **[[4l72]] – rDPP-IV + Mers-Cov Rbd<br /> | ||
**[[2gbc]] – rDPP-IV extracellular domain<br /> | **[[2gbc]] – rDPP-IV extracellular domain<br /> | ||
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*DPP-VI | *DPP-VI | ||
| - | **[[3pvq]] – DPP-VI – ''Bacterioides thetaiotamicron'' | + | **[[3pvq]], [[4r0k]] – DPP-VI – ''Bacterioides thetaiotamicron'' |
| + | |||
| + | *DPP-X | ||
| + | |||
| + | **[[4wjl]] – hDPP-X extracellular domain<br /> | ||
| + | |||
}} | }} | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 07:27, 25 March 2015
Dipeptidyl peptidase (DPP) is an enzyme which cleaves dipeptides from polypeptides.
- DPP-I is involved in inflammatory diseases.
- DPP-II is a serine protease.
- DPP-III acts similarly to DPP-IV.
- DPP-IV (or CD26) cleaves proline dipeptides from the N-termini and is associated with immune regulation.
See also
3D Structures of Dipeptidyl peptidase
Updated on 25-March-2015
