Microtubule-associated protein

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<StructureSection load='2jzd' size='340' side='right' caption='Human microtubule-associated protein light chain 3B complex with optineurin peptide (PDB code [[2lue]])' scene=''>
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<StructureSection load='2zjd' size='340' side='right' caption='Human microtubule-associated protein light chain 3B complex with optineurin peptide (PDB code [[2lue]])' scene=''>
'''Microtubule-associated protein light chain 3''' (LC3) is recruited to autophagosomal membranes during autophagy. The human LC3B is cleaved after synthesis to expose a C-terminal glycine which binds via a phospholipid anchor to autophagosomal vescicle membranes during autophagy. Thus detection of LC3 is a reliable method for monitoring autophagy.
'''Microtubule-associated protein light chain 3''' (LC3) is recruited to autophagosomal membranes during autophagy. The human LC3B is cleaved after synthesis to expose a C-terminal glycine which binds via a phospholipid anchor to autophagosomal vescicle membranes during autophagy. Thus detection of LC3 is a reliable method for monitoring autophagy.

Revision as of 09:37, 26 July 2015

Human microtubule-associated protein light chain 3B complex with optineurin peptide (PDB code 2lue)

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3D Structures of microtubule-associated protein light chain 3

Updated on 26-July-2015

References

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman, Jaime Prilusky

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