NADP-dependent malic enzyme

Best example is 1swy

Molecule Lysozyme, also known as Lysozyme, CP-7 lysin, Muramidase, Endolysin, 1,4-beta-N-acetylmuramidase, Lysis protein, CP-1 lysin, Lysozyme murein hydrolase, Protein gp17, Transglycosylase, Hevamine-A, Chitinase and L-alanyl-D-glutamate peptidase.

Function

lysozyme activity
catalytic activity
hydrolase activity
hydrolase activity, acting on glycosyl bonds
carbon-oxygen lyase activity, acting on polysaccharides
lyase activity
chitinase activity
hydrolase activity, hydrolyzing O-glycosyl compounds
sequence-specific DNA binding

Disease

Relevance

Structural highlights

Biological process

Is involved in the following biological processes:
cell wall macromolecule catabolic process
peptidoglycan catabolic process
metabolic process
defense response to bacterium
cytolysis
viral release from host cell
carbohydrate metabolic process
chitin catabolic process
polysaccharide catabolic process
cytolysis by virus of host cell
cell wall organization

In structures

Lysozyme is found in 595 PDB entries

*Eukaryota (16 PDB entries):

**Homo sapiens (1 PDB entries):

• • • 4uis
      
      
      Title: The cryoEM structure of human gamma-Secretase complex
      

Experimental EM map emd-2974.
4.4 A resolution
Other macromolecules also in this entry: GAMMA-SECRETASE, Nicastrin, Presenilin-1 NTF subunit, .



**Hevea brasiliensis (7 PDB entries):

• • • 1kqy
      
      
      Title: Hevamine Mutant D125A/E127A/Y183F in Complex with Penta-NAG
      

1.92 A resolution

"Hevea brasiliensis"&molecule_name:"Lysozyme" Search for other PDB entries

**Meretrix lusoria (3 PDB entries):

• • • 4pj2
      
      
      Title: Crystal structure of Aeromonas hydrophila PliI in complex with Meretrix lusoria lysozyme
      

1.24 A resolution
Other macromolecules also in this entry: Putative exported protein, .

"Meretrix lusoria"&molecule_name:"Lysozyme" Search for other PDB entries

**Antheraea mylitta (1 PDB entries):

• • • 1iiz
      
      
      Title: Crystal Structure of the Induced Antibacterial Protein from Tasar Silkworm, Antheraea mylitta
      

2.4 A resolution



**Ruditapes philippinarum (1 PDB entries):

• • • 2dqa
      
      
      Title: Crystal Structure of Tapes japonica Lysozyme
      

1.6 A resolution



**Mus musculus (1 PDB entries):

• • • 1iak
      
      
      Title: HISTOCOMPATIBILITY ANTIGEN I-AK
      

1.9 A resolution
Other macromolecules also in this entry: H-2 class II histocompatibility antigen, A-K beta chain, H-2 class II histocompatibility antigen, A-K alpha chain.



**Bombyx mori (2 PDB entries):

• • • 1gd6
      
      
      Title: STRUCTURE OF THE BOMBYX MORI LYSOZYME
      

2.5 A resolution

"Bombyx mori"&molecule_name:"Lysozyme" Search for other PDB entries

*Viruses (578 PDB entries):

**Enterobacteria phage P22 (2 PDB entries):

• • • 2anv
      
      
      Title: crystal structure of P22 lysozyme mutant L86M
      

1.04 A resolution

"Enterobacteria phage P22"&molecule_name:"Lysozyme" Search for other PDB entries

**Enterobacteria phage P21 (2 PDB entries):

• • • 3hdf
      
      
      Title: Crystal structure of truncated endolysin R21 from phage 21
      

1.7 A resolution

"Enterobacteria phage P21"&molecule_name:"Lysozyme" Search for other PDB entries

**Enterobacteria phage T4 (561 PDB entries):

• • • 1swy
      
      
      Title: Use of a Halide Binding Site to Bypass the 1000-atom Limit to Ab initio Structure Determination
      

1.06 A resolution

"Enterobacteria phage T4"&molecule_name:"Lysozyme" Search for other PDB entries

**Escherichia phage T5 (1 PDB entries):

• • • 2mxz
      
      
      Title: Bacteriophage T5 l-alanoyl-d-glutamate peptidase comlpex with Zn2+ (Endo T5-ZN2+)
      

N/A A resolution



**Enterobacteria phage lambda (3 PDB entries):

• • • 1am7
      
      
      Title: Lysozyme from bacteriophage lambda
      

2.3 A resolution

"Enterobacteria phage lambda"&molecule_name:"Lysozyme" Search for other PDB entries

**Streptococcus phage CP-7 (1 PDB entries):

• • • 4cvd
      
      
      Title: Crystal structure of the central repeat of cell wall binding module of Cpl7
      

1.666 A resolution



**Enterobacteria phage P1 (2 PDB entries):

• • • 1xju
      
      
      Title: Crystal structure of secreted inactive form of P1 phage endolysin Lyz
      

1.07 A resolution

"Enterobacteria phage P1"&molecule_name:"Lysozyme" Search for other PDB entries

**Streptococcus phage Cp-1 (6 PDB entries):

• • • 2j8g
      
      
      Title: Crystal structure of the modular Cpl-1 endolysin complexed with a peptidoglycan analogue (E94Q mutant in complex with a tetrasaccharide- pentapeptide)
      

1.69 A resolution

"Streptococcus phage Cp-1"&molecule_name:"Lysozyme" Search for other PDB entries

*Bacteria (1 PDB entries):

**Enterobacteria phage T4 (1 PDB entries):

• • • 2qb0
      
      
      Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.
      

2.56 A resolution
Other macromolecules also in this entry: Transcription factor ETV6, .



**Escherichia coli (1 PDB entries):

• • • 2qb0
      
      
      Title: Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker.
      

2.56 A resolution
Other macromolecules also in this entry: Transcription factor ETV6, .