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2ith

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<StructureSection load='2ith' size='340' side='right' caption='[[2ith]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2ith' size='340' side='right' caption='[[2ith]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2ith]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Haloferax_volcanii Haloferax volcanii]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ITH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ITH FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2ith]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_29605 Atcc 29605]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ITH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ITH FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">folA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2246 Haloferax volcanii])</td></tr>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">folA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2246 ATCC 29605])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ith FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ith OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ith RCSB], [http://www.ebi.ac.uk/pdbsum/2ith PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ith FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ith OCA], [http://pdbe.org/2ith PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ith RCSB], [http://www.ebi.ac.uk/pdbsum/2ith PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/DYR_HALVO DYR_HALVO]] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
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[[http://www.uniprot.org/uniprot/DYR_HALVD DYR_HALVD]] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2ith" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 29605]]
[[Category: Dihydrofolate reductase]]
[[Category: Dihydrofolate reductase]]
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[[Category: Haloferax volcanii]]
 
[[Category: Binbuga, B]]
[[Category: Binbuga, B]]
[[Category: Dhfr]]
[[Category: Dhfr]]
[[Category: Halophilic archaea]]
[[Category: Halophilic archaea]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]

Revision as of 05:01, 11 September 2015

NMR Structure of Haloferax volcanii DHFR

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