Dipeptidyl peptidase
From Proteopedia
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[[Dipeptidyl peptidase]] (DPP) is an enzyme which cleaves dipeptides from polypeptides.<br /> | [[Dipeptidyl peptidase]] (DPP) is an enzyme which cleaves dipeptides from polypeptides.<br /> | ||
| - | * '''DPP-I''' is involved in inflammatory diseases.<br /> | + | * '''DPP-I''' or '''cathepsin C''' is involved in inflammatory diseases.<br /> |
* '''DPP-II''' is a serine protease.<br /> | * '''DPP-II''' is a serine protease.<br /> | ||
* '''DPP-III''' acts similarly to DPP-IV.<br /> | * '''DPP-III''' acts similarly to DPP-IV.<br /> | ||
Revision as of 11:28, 30 December 2015
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3D Structures of Dipeptidyl peptidase
Updated on 30-December-2015
References
- ↑ Pro B, Dang NH. CD26/dipeptidyl peptidase IV and its role in cancer. Histol Histopathol. 2004 Oct;19(4):1345-51. PMID:15375776
- ↑ Barnett A. DPP-4 inhibitors and their potential role in the management of type 2 diabetes. Int J Clin Pract. 2006 Nov;60(11):1454-70. PMID:17073841 doi:10.1111/j.1742-1241.2006.01178.x
- ↑ Itou M, Kawaguchi T, Taniguchi E, Sata M. Dipeptidyl peptidase-4: a key player in chronic liver disease. World J Gastroenterol. 2013 Apr 21;19(15):2298-306. doi:, 10.3748/wjg.v19.i15.2298. PMID:23613622 doi:http://dx.doi.org/10.3748/wjg.v19.i15.2298
- ↑ Furber M, Tiden AK, Gardiner P, Mete A, Ford R, Millichip I, Stein L, Mather A, Kinchin E, Luckhurst C, Barber S, Cage P, Sanganee H, Austin R, Chohan K, Beri R, Thong B, Wallace A, Oreffo V, Hutchinson R, Harper S, Debreczeni J, Breed J, Wissler L, Edman K. Cathepsin C Inhibitors: Property Optimization and Identification of a Clinical Candidate. J Med Chem. 2014 Mar 14. PMID:24592859 doi:http://dx.doi.org/10.1021/jm401705g
