1bso
From Proteopedia
| Line 4: | Line 4: | ||
|PDB= 1bso |SIZE=350|CAPTION= <scene name='initialview01'>1bso</scene>, resolution 2.23Å | |PDB= 1bso |SIZE=350|CAPTION= <scene name='initialview01'>1bso</scene>, resolution 2.23Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand=BRC:12-BROMODODECANOIC ACID'>BRC</scene> | + | |LIGAND= <scene name='pdbligand=BRC:12-BROMODODECANOIC+ACID'>BRC</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bso OCA], [http://www.ebi.ac.uk/pdbsum/1bso PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1bso RCSB]</span> | ||
}} | }} | ||
| Line 26: | Line 29: | ||
[[Category: Jameson, G B.]] | [[Category: Jameson, G B.]] | ||
[[Category: Qin, B Y.]] | [[Category: Qin, B Y.]] | ||
| - | [[Category: BRC]] | ||
[[Category: beta-lactoglobulin]] | [[Category: beta-lactoglobulin]] | ||
[[Category: ligand binding]] | [[Category: ligand binding]] | ||
[[Category: x-ray crystal structure]] | [[Category: x-ray crystal structure]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 19:07:34 2008'' |
Revision as of 16:07, 30 March 2008
| |||||||
| , resolution 2.23Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | |||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
12-BROMODODECANOIC ACID BINDS INSIDE THE CALYX OF BOVINE BETA-LACTOGLOBULIN
Overview
The X-ray structure of bovine beta-lactoglobulin with the ligand 12-bromododecanoic acid as a model for fatty acids has been determined at a resolution of 2.23 A in the trigonal lattice Z form. The ligand binds inside the calyx, resolving a long-standing controversy as to where fatty-acid like ligands bind. The carboxylate head group lies at the surface of the molecule, and the lid to the calyx is open at the pH of crystallization (pH 7.3), consistent with the conformation observed in ligand-free bovine beta-lactoglobulin in lattice Z at pH 7.1 and pH 8.2.
About this Structure
1BSO is a Single protein structure of sequence from Bos taurus. Full crystallographic information is available from OCA.
Reference
12-Bromododecanoic acid binds inside the calyx of bovine beta-lactoglobulin., Qin BY, Creamer LK, Baker EN, Jameson GB, FEBS Lett. 1998 Nov 6;438(3):272-8. PMID:9827560
Page seeded by OCA on Sun Mar 30 19:07:34 2008
