Fatty acid synthase
From Proteopedia
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== Structural insights == | == Structural insights == | ||
| - | The long fatty acid ligand is nestled in a long groove and tunnel<ref>PMID:21908709</ref>. | + | <scene name='48/484817/Cv/3'>Active site predominantly consists of hydrophobic/non-polar residues</scene>. The long fatty acid ligand is nestled in a long groove and tunnel<ref>PMID:21908709</ref>. |
</StructureSection> | </StructureSection> | ||
Revision as of 11:14, 25 January 2016
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3D structures of fatty acid synthase
Updated on 25-January-2016
References
- ↑ Smith S, Witkowski A, Joshi AK. Structural and functional organization of the animal fatty acid synthase. Prog Lipid Res. 2003 Jul;42(4):289-317. PMID:12689621
- ↑ Zhang W, Chakravarty B, Zheng F, Gu Z, Wu H, Mao J, Wakil SJ, Quiocho FA. Crystal structure of FAS thioesterase domain with polyunsaturated fatty acyl adduct and inhibition by dihomo-{gamma}-linolenic acid. Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):15757-62. Epub 2011 Sep 9. PMID:21908709 doi:10.1073/pnas.1112334108
