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(New page: {{Sandbox_Reserved_CH462_Central_Metabolism}}<!-- PLEASE ADD YOUR CONTENT BELOW HERE --> ==Your Heading Here (maybe something like 'Structure')== <StructureSection load='1stp' size='340' s...) |
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| - | + | <math></math><includeonly></includeonly>==Human GPR40, also known as Free Fatty Acid Receptor 1 (FFAR1)== | |
| - | == | + | <StructureSection load='Sele4phu.pdb' size='340' side='right' caption='hGPR40' scene='72/726431/General_protein/1'> |
| - | <StructureSection load=' | + | |
| - | + | ||
| - | + | == Background == | |
| + | |||
| + | == Structure == | ||
| + | [[Image:4phutopviewlabels.png |200 px|right|thumb|Figure Legend]] | ||
| + | |||
| + | <scene name='72/721542/Transmembrane_helices/2'>seven transmembrane helices</scene> | ||
| + | <scene name='72/721542/Top_view_transmembrane_helices/2'>top view of TM helices</scene> | ||
| + | |||
| + | === Binding Sites === | ||
| + | <scene name='72/721542/Tak_binding_site/3'>Tak-875 Binding Site</scene> | ||
| + | [[Image:4phuBind2.png|200 px|right|thumb|Figure 2. Second proposed binding site of GPR40. By visual inspection, a second possible binding site was proposed between transmembrane helices 3, 4, and 5 on the intracellular side.]] | ||
| + | [[Image:4phubind3.png|200 px|right|thumb|Figure 3. Third proposed binding site of GPR40. By visual inspection, a third possible binding site was proposed between transmembrane helices 1, 2, and 7 on the extracellular side.]] | ||
| + | |||
| + | === Ionic Charge Network === | ||
| + | |||
| + | === ECL2 === | ||
| + | |||
| + | [https://en.wikipedia.org/wiki/Beta_sheet beta sheet] | ||
== Function == | == Function == | ||
| - | == | + | == Clinical Relevance == |
| - | == | + | === Tak-875 === |
| + | [[Image:Tak-875.png |300 px|right|Figure Legend]] | ||
| + | <scene name='72/721542/Tak875/2'>Tak-875</scene> | ||
| - | == Structural highlights == | ||
| - | This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | ||
</StructureSection> | </StructureSection> | ||
== References == | == References == | ||
<references/> | <references/> | ||
Current revision
<math></math>==Human GPR40, also known as Free Fatty Acid Receptor 1 (FFAR1)==
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