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Nonstructural protein

From Proteopedia

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== Structural highlights ==
== Structural highlights ==
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Hepatitis virus NS active site shows hydrogen bond interactions and hydrophobic pocket interactions<ref>PMID:12509436</ref>.
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<scene name='46/461364/Cv/3'>Hepatitis virus NS active site shows hydrogen bond interactions and hydrophobic pocket interactions</scene><ref>PMID:12509436</ref>.
</StructureSection>
</StructureSection>

Revision as of 07:26, 18 May 2016

Hepatitis virus nonstructural protein complex with non-nucleoside analogue inhibitor (PDB entry 1nhu)

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3D Structures of Nonstructural protein

Updated on 18-May-2016

References

  1. ↑ Zhu Z, Shi Z, Yan W, Wei J, Shao D, Deng X, Wang S, Li B, Tong G, Ma Z. Nonstructural protein 1 of influenza A virus interacts with human guanylate-binding protein 1 to antagonize antiviral activity. PLoS One. 2013;8(2):e55920. doi: 10.1371/journal.pone.0055920. Epub 2013 Feb 6. PMID:23405236 doi:http://dx.doi.org/10.1371/journal.pone.0055920
  2. ↑ Wang M, Ng KK, Cherney MM, Chan L, Yannopoulos CG, Bedard J, Morin N, Nguyen-Ba N, Alaoui-Ismaili MH, Bethell RC, James MN. Non-nucleoside analogue inhibitors bind to an allosteric site on HCV NS5B polymerase. Crystal structures and mechanism of inhibition. J Biol Chem. 2003 Mar 14;278(11):9489-95. Epub 2002 Dec 30. PMID:12509436 doi:10.1074/jbc.M209397200

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Michal Harel, Alexander Berchansky

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