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Opioid receptor

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* The '''κ-opioid receptor''' binds opium-type ligands. For details see [[Student Project 3 for UMass Chemistry 423 Spring 2015]].<br />
* The '''κ-opioid receptor''' binds opium-type ligands. For details see [[Student Project 3 for UMass Chemistry 423 Spring 2015]].<br />
* The '''δ-opioid receptor''' binds enkephalins. For details see [[Delta opioid receptor]].
* The '''δ-opioid receptor''' binds enkephalins. For details see [[Delta opioid receptor]].
 +
* The '''Nociceptin/orphanin FQ opioid receptor''' binds the heptadecapeptide orphanin<ref>PMID:23395957</ref>.
== Relevance ==
== Relevance ==

Revision as of 08:32, 9 June 2016

Structure of κ-opioid receptor complex with opioid antagonist, citric acid, PEG and octadec-enoate derivative (PDB entry 4djh)

Drag the structure with the mouse to rotate

3D structures of opioid receptor

Updated on 09-June-2016

References

  1. ↑ Feng Y, He X, Yang Y, Chao D, Lazarus LH, Xia Y. Current research on opioid receptor function. Curr Drug Targets. 2012 Feb;13(2):230-46. PMID:22204322
  2. ↑ Donica CL, Awwad HO, Thakker DR, Standifer KM. Cellular mechanisms of nociceptin/orphanin FQ (N/OFQ) peptide (NOP) receptor regulation and heterologous regulation by N/OFQ. Mol Pharmacol. 2013 May;83(5):907-18. doi: 10.1124/mol.112.084632. Epub 2013 Feb , 8. PMID:23395957 doi:http://dx.doi.org/10.1124/mol.112.084632
  3. ↑ Zaveri NT. The nociceptin/orphanin FQ receptor (NOP) as a target for drug abuse medications. Curr Top Med Chem. 2011;11(9):1151-6. PMID:21050175
  4. ↑ Chiou LC, Liao YY, Fan PC, Kuo PH, Wang CH, Riemer C, Prinssen EP. Nociceptin/orphanin FQ peptide receptors: pharmacology and clinical implications. Curr Drug Targets. 2007 Jan;8(1):117-35. PMID:17266536

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