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RNA ligase

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[[1iuh]] – LigR 2’-5’ – ''Thermus thermophilus''<br />
[[1iuh]] – LigR 2’-5’ – ''Thermus thermophilus''<br />
[[4qak]] - LigR 2’-5’ – ''Escherichia coli''<br />
[[4qak]] - LigR 2’-5’ – ''Escherichia coli''<br />
 +
[[5cot]] – aLigR – amoeba<br />
 +
[[5cou]] – aLigR + ATP<br />
 +
[[5d1o]], [[5d1p]] – LigR ATP-dependent + ATP – ''Methanothermobacter thermautotrophicus''<br />
 +
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 08:22, 18 August 2016

Template:STRUCTURE 1vgj

RNA ligase (LigR) is an enzyme which ligates two ribonucleotide chains using ATP and producing AMP, diphosphate and the ligated ribonucleotide chain[1]. See more details in T4 RNA ligase 2 (Rnl2) and Ligases.


3D Structures of RNA ligase

Updated on 18-August-2016

2hvr, 2hvs – T4LigR 2 + DNA + nucleotide – Enterobacteria phage T4
1s68 - T4LigR 2 N-terminal
2c5u – T4LigR 1 RNA-binding domain
1vgj, 1vdx – LigR – Pyrococcus horikoshii
2vug – LigR – Pyrococcus abyssi
1xdn – LigR 1 editing – Trypanosoma brucei
1iuh – LigR 2’-5’ – Thermus thermophilus
4qak - LigR 2’-5’ – Escherichia coli
5cot – aLigR – amoeba
5cou – aLigR + ATP
5d1o, 5d1p – LigR ATP-dependent + ATP – Methanothermobacter thermautotrophicus

References

  1. Nichols NM, Tabor S, McReynolds LA. RNA ligases. Curr Protoc Mol Biol. 2008 Oct;Chapter 3:Unit3.15. doi:, 10.1002/0471142727.mb0315s84. PMID:18972386 doi:http://dx.doi.org/10.1002/0471142727.mb0315s84

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Michal Harel, Joel L. Sussman, Alexander Berchansky

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