Nonstructural protein

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**[[2ajj]], [[2ajm]], [[2ajn]], [[2ajo]] – NS5A membrane-anchor domain – bovine viral diarrhea virus – NMR<br />
**[[2ajj]], [[2ajm]], [[2ajn]], [[2ajo]] – NS5A membrane-anchor domain – bovine viral diarrhea virus – NMR<br />
**[[1fw5]] – NSP1 membrane-binding domain – Semliki forest virus – NMR<br />
**[[1fw5]] – NSP1 membrane-binding domain – Semliki forest virus – NMR<br />
 +
**[[5vj2]] – NS1 – respiratory syncytial virus<br />
 +
**[[5i65]] – NS ORF1A – porcine reproductive and respiratory syndrome virus<br />
**[[1qol]] – NSP20A (mutant) - Foot-and-mouth disease virus<br />
**[[1qol]] – NSP20A (mutant) - Foot-and-mouth disease virus<br />
**[[1nhu]] – HvNS5B RNA-dependent RNA polymerase residues 2420-2989 – Hepatitis C virus<br />
**[[1nhu]] – HvNS5B RNA-dependent RNA polymerase residues 2420-2989 – Hepatitis C virus<br />
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**[[2xbm]] – DvNS5 methyltransferase domain + RNA<br />
**[[2xbm]] – DvNS5 methyltransferase domain + RNA<br />
**[[3p8z]] - DvNS5 methyltransferase domain + SAH + inhibitor<br />
**[[3p8z]] - DvNS5 methyltransferase domain + SAH + inhibitor<br />
 +
**[[5cuq]] - DvNS5 methyltransferase domain + inhibitor<br />
 +
**[[5fc8]] - DvNS5 C-terminal + importin<br />
**[[2hye]] – SvNSV + DNA damage-binding protein + cullin-4A + ring-box protein – Simian virus 5<br />
**[[2hye]] – SvNSV + DNA damage-binding protein + cullin-4A + ring-box protein – Simian virus 5<br />
**[[2b5l]] - SvNSV + DNA damage-binding protein<br />
**[[2b5l]] - SvNSV + DNA damage-binding protein<br />

Revision as of 09:48, 27 August 2017

Hepatitis virus nonstructural protein complex with non-nucleoside analogue inhibitor (PDB entry 1nhu)

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3D Structures of Nonstructural protein

Updated on 27-August-2017

References

  1. Zhu Z, Shi Z, Yan W, Wei J, Shao D, Deng X, Wang S, Li B, Tong G, Ma Z. Nonstructural protein 1 of influenza A virus interacts with human guanylate-binding protein 1 to antagonize antiviral activity. PLoS One. 2013;8(2):e55920. doi: 10.1371/journal.pone.0055920. Epub 2013 Feb 6. PMID:23405236 doi:http://dx.doi.org/10.1371/journal.pone.0055920
  2. Wang M, Ng KK, Cherney MM, Chan L, Yannopoulos CG, Bedard J, Morin N, Nguyen-Ba N, Alaoui-Ismaili MH, Bethell RC, James MN. Non-nucleoside analogue inhibitors bind to an allosteric site on HCV NS5B polymerase. Crystal structures and mechanism of inhibition. J Biol Chem. 2003 Mar 14;278(11):9489-95. Epub 2002 Dec 30. PMID:12509436 doi:10.1074/jbc.M209397200

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Michal Harel, Alexander Berchansky

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