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Sandbox k11v
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| - | == | + | ==Toxic Amyloid Small Oligomer’s atomic view== |
| - | <StructureSection load=' | + | <StructureSection load='2wj7' size='340' side='right' caption='Structure of alpha-beta crystallin.' scene=''> |
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| + | Amyloid fibrils were suspected for long to be the agents of Amyloid diseases,including Alzheimer’s,Parkinson’s and the prion conditions.But evidence suggests that smaller, often transient and polymorphic oligomers are the toxic entities.Segment of amyloid forming protein alpha-beta crystallin makes oligomeric complex which exhibits properties of other amyloid oligomers.The structure of oligomer shows a cylindrical barrel,made up of six anti-parallel protein strands known as cylindrin.This segment termed as K11V forms the cylindrin structure. | ||
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PDB'S are | PDB'S are | ||
K11V (<scene name='77/771966/3sgo/1'>3SGO</scene>), K11V-Br2 (<scene name='77/771966/3sgm/1'>3SGM</scene>), K11V-Br8 (<scene name='77/771966/3sgn/1'>3SGN</scene>), K11VV2L (<scene name='77/771966/3sgp/1'>3SGP</scene>), K11V-TR (<scene name='77/771966/3sgr/1'>3SGR</scene>), and GDVIEV (<scene name='77/771966/3sgs/1'>3SGS</scene>). | K11V (<scene name='77/771966/3sgo/1'>3SGO</scene>), K11V-Br2 (<scene name='77/771966/3sgm/1'>3SGM</scene>), K11V-Br8 (<scene name='77/771966/3sgn/1'>3SGN</scene>), K11VV2L (<scene name='77/771966/3sgp/1'>3SGP</scene>), K11V-TR (<scene name='77/771966/3sgr/1'>3SGR</scene>), and GDVIEV (<scene name='77/771966/3sgs/1'>3SGS</scene>). | ||
Revision as of 06:35, 4 November 2017
Toxic Amyloid Small Oligomer’s atomic view
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