Amino acid oxidase

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<StructureSection load='2jb1' size='350' side='right' scene='48/486454/Cv/1' caption='L-amino acid oxidase dimer containing FAD complex with alanine, [[2jb1]]'>
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<StructureSection load='2jb1' size='400' side='right' scene='48/486454/Cv/1' caption='L-amino acid oxidase dimer containing FAD complex with alanine, [[2jb1]]'>
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== Structural highlights ==
== Structural highlights ==
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LAO structure contains 3 domains: <scene name='48/486454/Cv/5'>FAD-binding, substrate-binding and helical</scene> domains. <scene name='48/486454/Cv/6'>Active site</scene> of L-amino acid oxidase ([[2jb1]]).<ref>PMID:17234209</ref>
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LAO structure contains 3 domains: <scene name='48/486454/Cv/5'>FAD-binding, substrate-binding and helical</scene> domains. <scene name='48/486454/Cv/6'>Active site</scene> of L-amino acid oxidase ([[2jb1]]).<ref>PMID:17234209</ref> Water molecules are shown as red spheres.
</StructureSection>
</StructureSection>
==3D structures of amino acid oxidase==
==3D structures of amino acid oxidase==

Revision as of 12:00, 2 May 2018

L-amino acid oxidase dimer containing FAD complex with alanine, 2jb1

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3D structures of amino acid oxidase

Updated on 02-May-2018

References

  1. Du XY, Clemetson KJ. Snake venom L-amino acid oxidases. Toxicon. 2002 Jun;40(6):659-65. PMID:12175601
  2. Pollegioni L, Piubelli L, Sacchi S, Pilone MS, Molla G. Physiological functions of D-amino acid oxidases: from yeast to humans. Cell Mol Life Sci. 2007 Jun;64(11):1373-94. PMID:17396222 doi:http://dx.doi.org/10.1007/s00018-007-6558-4
  3. Faust A, Niefind K, Hummel W, Schomburg D. The structure of a bacterial L-amino acid oxidase from Rhodococcus opacus gives new evidence for the hydride mechanism for dehydrogenation. J Mol Biol. 2007 Mar 16;367(1):234-48. Epub 2006 Dec 1. PMID:17234209 doi:http://dx.doi.org/10.1016/j.jmb.2006.11.071

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Michal Harel, Alexander Berchansky

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