Sandbox1014
From Proteopedia
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==Your Heading Here (maybe something like 'Structure')== | ==Your Heading Here (maybe something like 'Structure')== | ||
<StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''> | <StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''> | ||
| + | <Structure load='4ny4' size='350' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' /> | ||
== Overview== | == Overview== | ||
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Cytochrome P450 3A4 (CYP3A4) is in the heme-thiolate monooxygenase enzyme family meaning the protein contains a heme group with an iron atom. Enzymes in Cytochrome P450 are oxidizing enzymes and CYP3A4 works in the body oxidizing foreign molecules such as toxins and drugs[1][2]. It appears almost half of the marketed pharmaceutical drugs are metabolized by CYP3A4 [1] All Cytochrome P450 are essential enzymes for metabolism and the enzyme CYP3A4 is the most important. [2] Primarily found in the liver and intestine, CYP3A4 is localized in the endoplasmic reticulum membrane [3] and are present in all eukaryotic organisms as well as some prokaryotes[3]. While CYP3A4's role in drug metabolism are numerous, they are often aiding deactivation through facilitated excretion from the system or by direct inactivation. | Cytochrome P450 3A4 (CYP3A4) is in the heme-thiolate monooxygenase enzyme family meaning the protein contains a heme group with an iron atom. Enzymes in Cytochrome P450 are oxidizing enzymes and CYP3A4 works in the body oxidizing foreign molecules such as toxins and drugs[1][2]. It appears almost half of the marketed pharmaceutical drugs are metabolized by CYP3A4 [1] All Cytochrome P450 are essential enzymes for metabolism and the enzyme CYP3A4 is the most important. [2] Primarily found in the liver and intestine, CYP3A4 is localized in the endoplasmic reticulum membrane [3] and are present in all eukaryotic organisms as well as some prokaryotes[3]. While CYP3A4's role in drug metabolism are numerous, they are often aiding deactivation through facilitated excretion from the system or by direct inactivation. | ||
| - | 시토크롬P450 3A4(CYP3A4)는 헴-타이오레이트 모노옥시게나아제 효소의 패밀리에 속합니다. 이 패밀리는 철 원자를 가지고 있는 헴 그룹을 포함합니다. | + | 시토크롬P450 3A4(CYP3A4)는 헴-타이오레이트 모노옥시게나아제 효소의 패밀리에 속합니다. 이 패밀리는 철 원자를 가지고 있는 헴 그룹을 포함합니다.adf |
== Mechanism == | == Mechanism == | ||
Revision as of 06:16, 18 July 2018
Your Heading Here (maybe something like 'Structure')
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