Amino acid oxidase
From Proteopedia
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LAO structure contains 3 domains: <scene name='48/486454/Cv/5'>FAD-binding, substrate-binding and helical</scene> domains. <scene name='48/486454/Cv/6'>Active site</scene> of L-amino acid oxidase ([[2jb1]]).<ref>PMID:17234209</ref> Water molecules are shown as red spheres. | LAO structure contains 3 domains: <scene name='48/486454/Cv/5'>FAD-binding, substrate-binding and helical</scene> domains. <scene name='48/486454/Cv/6'>Active site</scene> of L-amino acid oxidase ([[2jb1]]).<ref>PMID:17234209</ref> Water molecules are shown as red spheres. | ||
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| + | ==3D structures of amino acid oxidase== | ||
| + | [[Amino acid oxidase 3D structures]] | ||
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</StructureSection> | </StructureSection> | ||
==3D structures of amino acid oxidase== | ==3D structures of amino acid oxidase== | ||
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**[[1ve9]] - pDAO + benzoate<br /> | **[[1ve9]] - pDAO + benzoate<br /> | ||
**[[1evi]] – pDAO + dihydro-pyrrolium-carboxylate<br /> | **[[1evi]] – pDAO + dihydro-pyrrolium-carboxylate<br /> | ||
| + | **[[5wwv]], [[5wx2]] - pDAO (mutant) + chlorobenzhydrylamine<br /> | ||
**[[1c0k]] – RtDAO + L-lactate<br /> | **[[1c0k]] – RtDAO + L-lactate<br /> | ||
**[[1c0p]] – RtDAO + peroxide<br /> | **[[1c0p]] – RtDAO + peroxide<br /> | ||
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**[[2e49]] - hDAO + iminoserine <br /> | **[[2e49]] - hDAO + iminoserine <br /> | ||
**[[2e82]] - hDAO + imino-DOPA <br /> | **[[2e82]] - hDAO + imino-DOPA <br /> | ||
| - | **[[3cuk]], [[3w4i]], [[3w4j]], [[3w4k]], [[3znn]], [[3zno]], [[3znp]], [[3znq]], [[4qfc]], [[4qfd]] - hDAO + inhibitor <br /> | + | **[[3cuk]], [[3w4i]], [[3w4j]], [[3w4k]], [[3znn]], [[3zno]], [[3znp]], [[3znq]], [[4qfc]], [[4qfd]], [[5zj9]], [[5zja]] - hDAO + inhibitor <br /> |
**[[3g3e]] - hDAO + hydroxyquinoline<br /> | **[[3g3e]] - hDAO + hydroxyquinoline<br /> | ||
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**[[4cnj]], [[4cnk]] – LAO + FAD – ''Streptococcus oligofermentans''<br /> | **[[4cnj]], [[4cnk]] – LAO + FAD – ''Streptococcus oligofermentans''<br /> | ||
**[[5hxv]], [[5i39]] – LAO + FAD - ''Proteus vulgaris'' <br /> | **[[5hxv]], [[5i39]] – LAO + FAD - ''Proteus vulgaris'' <br /> | ||
| + | **[[5z2g]] – LAO + FAD – ''Naja atra''<br /> | ||
*L-amino acid oxidase complex | *L-amino acid oxidase complex | ||
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*L-amino acid oxidase/monooxigenase | *L-amino acid oxidase/monooxigenase | ||
| - | **[[ | + | **[[3we0]] - PsLAO + FAD – ''Pseudomonas''<br /> |
**[[5yb6]] - PsLAO + FAD + L-lysine<br /> | **[[5yb6]] - PsLAO + FAD + L-lysine<br /> | ||
**[[5yb7]] - PsLAO + FAD + L-ornithine<br /> | **[[5yb7]] - PsLAO + FAD + L-ornithine<br /> | ||
Revision as of 09:44, 6 March 2019
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3D structures of amino acid oxidase
Updated on 06-March-2019
References
- ↑ Du XY, Clemetson KJ. Snake venom L-amino acid oxidases. Toxicon. 2002 Jun;40(6):659-65. PMID:12175601
- ↑ Pollegioni L, Piubelli L, Sacchi S, Pilone MS, Molla G. Physiological functions of D-amino acid oxidases: from yeast to humans. Cell Mol Life Sci. 2007 Jun;64(11):1373-94. PMID:17396222 doi:http://dx.doi.org/10.1007/s00018-007-6558-4
- ↑ Faust A, Niefind K, Hummel W, Schomburg D. The structure of a bacterial L-amino acid oxidase from Rhodococcus opacus gives new evidence for the hydride mechanism for dehydrogenation. J Mol Biol. 2007 Mar 16;367(1):234-48. Epub 2006 Dec 1. PMID:17234209 doi:http://dx.doi.org/10.1016/j.jmb.2006.11.071
