This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Fatty acid synthase
From Proteopedia
(Difference between revisions)
| Line 10: | Line 10: | ||
== Structural insights == | == Structural insights == | ||
| - | <scene name='48/484817/Cv/ | + | <scene name='48/484817/Cv/6'>Active site predominantly consists of hydrophobic/non-polar residues</scene> ({{Template:ColorKey_Hydrophobic}}, {{Template:ColorKey_Polar}}). The <scene name='48/484817/Cv/7'>long fatty acid ligand is nestled in a long groove and tunnel</scene><ref>PMID:21908709</ref>. |
</StructureSection> | </StructureSection> | ||
Revision as of 11:02, 17 March 2019
| |||||||||||
3D structures of fatty acid synthase
Updated on 17-March-2019
References
- ↑ Smith S, Witkowski A, Joshi AK. Structural and functional organization of the animal fatty acid synthase. Prog Lipid Res. 2003 Jul;42(4):289-317. PMID:12689621
- ↑ Zhang W, Chakravarty B, Zheng F, Gu Z, Wu H, Mao J, Wakil SJ, Quiocho FA. Crystal structure of FAS thioesterase domain with polyunsaturated fatty acyl adduct and inhibition by dihomo-{gamma}-linolenic acid. Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):15757-62. Epub 2011 Sep 9. PMID:21908709 doi:10.1073/pnas.1112334108
