Deoxycytidine kinase

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== 3D Structures of deoxycytidine kinase ==
 
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 
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{{#tree:id=OrganizedByTopic|openlevels=0|
 
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*dCK complex with chemotherapy agent
 
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**[[1p5z]], [[1p62]], [[2a7q]] – hDCK + ADP + chemotherapy agent – human<br />
 
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**[[2no9]], [[2noa]], [[2no0]], [[2no6]], [[2zi9]] – hDCK (mutant) + ADP + chemotherapy agent <br />
 
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**[[2zia]], [[4kcg]] – hDCK (mutant) + UDP + chemotherapy agent <br />
 
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**[[5mqi]], [[5mqt]], [[5mql]] – hDCK (mutant) + UDP + dCMP + chemotherapy agent<br />
 
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*dCK complex with nucleoside
 
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**[[1p60]], [[1p61]], [[3kfx]] – hDCK + ADP + dC<br />
 
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**[[2no1]], [[2no7]] – hDCK (mutant) + ADP + dC<br />
 
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**[[2zi3]], [[2zi4]] – hDCK (mutant) + ADP + dA<br />
 
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**[[3hp1]] – hDCK (mutant) + ADP + dT<br />
 
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**[[2zi5]], [[2zi6]] – hDCK (mutant) + UDP + dA<br />
 
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**[[2zi7]] – hDCK (mutant) + UDP + dG<br />
 
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**[[2a2z]], [[3qen]] – hDCK (mutant) + UDP + dC<br />
 
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**[[3qeo]] – hDCK (mutant) + UDP + dT<br />
 
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**[[2a30]] – hDCK (mutant) + dC<br />
 
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**[[5mqj]] – hDCK (mutant) + UDP + UMP<br />
 
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*Other dCK complexes
 
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**[[2qrn]] – hDCK + UDP + CMP<br />
 
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**[[2qro]] – hDCK + UDP + AMP<br />
 
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**[[3ipx]] – hDCK + ADP + inhibitor<br />
 
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**[[3ipy]] – hDCK + inhibitor<br />
 
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**[[3qej]] – hDCK (mutant) + UDP <br />
 
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**[[4jlj]], [[4jlk]], [[4jlm]], [[4jln]], [[4l5b]], [[4q18]], [[4q19]], [[4q1a]], [[4q1b]], [[4q1c]], [[4q1d]], [[4q1e]], [[4q1f]] - hDCK (mutant) + UDP + inhibitor<br />
 
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**[[3mjr]] – hDCK + UDP + hydroxyethoxymethylguanine<br />
 
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}}
 
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 08:44, 5 June 2019

Mouse deoxycytidine kinase complex with ADP and deoxycytidine (PDB entry 1p61)

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References

  1. ↑ Hazra S, Ort S, Konrad M, Lavie A. Structural and kinetic characterization of human deoxycytidine kinase variants able to phosphorylate 5-substituted deoxycytidine and thymidine analogues . Biochemistry. 2010 Aug 10;49(31):6784-90. PMID:20614893 doi:10.1021/bi100839e
  2. ↑ Sabini E, Ort S, Monnerjahn C, Konrad M, Lavie A. Structure of human dCK suggests strategies to improve anticancer and antiviral therapy. Nat Struct Biol. 2003 Jul;10(7):513-9. PMID:12808445 doi:http://dx.doi.org/10.1038/nsb942

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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