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7ojt
From Proteopedia
(Difference between revisions)
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==Crystal structure of unliganded PatA, a membrane associated acyltransferase from Mycobacterium smegmatis== | ==Crystal structure of unliganded PatA, a membrane associated acyltransferase from Mycobacterium smegmatis== | ||
| - | <StructureSection load='7ojt' size='340' side='right'caption='[[7ojt]]' scene=''> | + | <StructureSection load='7ojt' size='340' side='right'caption='[[7ojt]], [[Resolution|resolution]] 3.67Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7OJT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7OJT FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7ojt]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7OJT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7OJT FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ojt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ojt OCA], [https://pdbe.org/7ojt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ojt RCSB], [https://www.ebi.ac.uk/pdbsum/7ojt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ojt ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> |
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Phosphatidylinositol_dimannoside_acyltransferase Phosphatidylinositol dimannoside acyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.265 2.3.1.265] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ojt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ojt OCA], [https://pdbe.org/7ojt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ojt RCSB], [https://www.ebi.ac.uk/pdbsum/7ojt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ojt ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/ACYLT_MYCS2 ACYLT_MYCS2]] Catalyzes the acylation to the position 6 of the alpha-1,2-linked mannose residue of the phosphatidyl-myo-inositol dimannoside (PIM2) or monomannoside (PIM1).<ref>PMID:12851411</ref> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | [Figure: see text]. | ||
| + | |||
| + | Molecular ruler mechanism and interfacial catalysis of the integral membrane acyltransferase PatA.,Anso I, Basso LGM, Wang L, Marina A, Paez-Perez ED, Jager C, Gavotto F, Tersa M, Perrone S, Contreras FX, Prandi J, Gilleron M, Linster CL, Corzana F, Lowary TL, Trastoy B, Guerin ME Sci Adv. 2021 Oct 15;7(42):eabj4565. doi: 10.1126/sciadv.abj4565. Epub 2021 Oct, 15. PMID:34652941<ref>PMID:34652941</ref> | ||
| + | |||
| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 7ojt" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Anso I]] | + | [[Category: Phosphatidylinositol dimannoside acyltransferase]] |
| - | [[Category: Guerin | + | [[Category: Anso, I]] |
| - | [[Category: Lowary | + | [[Category: Guerin, M E]] |
| - | [[Category: Marina A]] | + | [[Category: Lowary, T L]] |
| - | [[Category: Paez-Perez | + | [[Category: Marina, A]] |
| - | [[Category: Perrone S]] | + | [[Category: Paez-Perez, E D]] |
| - | [[Category: Trastoy B]] | + | [[Category: Perrone, S]] |
| - | [[Category: Wang L]] | + | [[Category: Trastoy, B]] |
| + | [[Category: Wang, L]] | ||
| + | [[Category: Acyltrasnferase]] | ||
| + | [[Category: Integral membrane protein transferase]] | ||
| + | [[Category: Mycobacteria]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 16:02, 3 November 2021
Crystal structure of unliganded PatA, a membrane associated acyltransferase from Mycobacterium smegmatis
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