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Akt/PKB signaling pathway
From Proteopedia
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The Akt signaling pathway or PI3K-Akt signaling pathway is a signal transduction pathway that promotes survival and growth in response to extracellular signals. Key proteins involved are PI3K ([[phosphatidylinositol 3-kinase]]) and Akt (protein kinase B). See also [[Signal transduction]]. | The Akt signaling pathway or PI3K-Akt signaling pathway is a signal transduction pathway that promotes survival and growth in response to extracellular signals. Key proteins involved are PI3K ([[phosphatidylinositol 3-kinase]]) and Akt (protein kinase B). See also [[Signal transduction]]. | ||
| + | =Activation Akt/PKB via Receptor tyrosine kinases/Ras= | ||
| + | ==[[Receptor tyrosine kinases]]== | ||
| + | ==Ras activation== | ||
| + | [[GTPase KRas]] | ||
| + | |||
| + | [[Allosteric modulation of H-Ras GTPase]] | ||
</StructureSection> | </StructureSection> | ||
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 11:08, 1 March 2022
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