Canine parvovirus

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<StructureSection load='A5.pdb' size='500' side='right' scene='Canine_parvovirus/Cv/9' caption=''>
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<StructureSection load='4dpv' size='350' side='right' scene='' caption='Parvovirus coat protein complex with DNA (pink) and Mg+2 ions (green) (PDB code [[4dpv]])'>
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The DNA-containing capsid of canine parvovirus (CPV) contains 60 copies of the capsid protein related by icosahedral symmetry. <scene name='Canine_parvovirus/Cv/7'>Each capsomer</scene> has 5-fold
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== Function ==
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The DNA-containing capsid of '''canine parvovirus''' (CPV) contains 60 copies of the capsid protein related by icosahedral symmetry. See also [[Viral capsids]].
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== Disease ==
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The virus causes the parvo disease in dogs which is fatal if untreated.
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== Structural highlights ==
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<scene name='Canine_parvovirus/Cv/10'>Each capsid protein</scene> participates in formation of <scene name='Canine_parvovirus/Cv/11'>5-fold</scene> and <scene name='Canine_parvovirus/Cv/12'>23-fold symmetry</scene>. <scene name='Canine_parvovirus/Cv/13'>Click here to see morph explaining this.</scene> Based on PDB entry [[4dpv]]<ref>PMID:8969301</ref>.
</StructureSection>
</StructureSection>
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==3D structures of canine parvovirus==
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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[[2cas]], [[1c8d]], [[1c8h]] – Empty capsid protein 2<br />
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[[7m3m]], [[7m3o]] - capsid protein 2 – Cryo EM<br />
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[[3jcx]], [[7m3l]], [[7m3n]] - capsid protein 2 + antibody – Cryo EM<br />
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[[4qyk]] - variant<br />
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[[6oas]] - Vp1 - Cryo EM<br />
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[[1p5y]], [[1p5w]] – Vp2<br />
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[[1ijs]], [[4dpv]] – Protein 2 + DNA<br />
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[[Category:Topic Page]]
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== References ==
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<references/>

Current revision

Parvovirus coat protein complex with DNA (pink) and Mg+2 ions (green) (PDB code 4dpv)

Drag the structure with the mouse to rotate

3D structures of canine parvovirus

Updated on 13-November-2022

2cas, 1c8d, 1c8h – Empty capsid protein 2
7m3m, 7m3o - capsid protein 2 – Cryo EM
3jcx, 7m3l, 7m3n - capsid protein 2 + antibody – Cryo EM
4qyk - variant
6oas - Vp1 - Cryo EM
1p5y, 1p5w – Vp2
1ijs, 4dpv – Protein 2 + DNA


References

  1. ↑ Xie Q, Chapman MS. Canine parvovirus capsid structure, analyzed at 2.9 A resolution. J Mol Biol. 1996 Dec 6;264(3):497-520. PMID:8969301 doi:10.1006/jmbi.1996.0657

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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