This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
7rww
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Crystal structure of a Zn-bound RIDC1 variant== | ==Crystal structure of a Zn-bound RIDC1 variant== | ||
| - | <StructureSection load='7rww' size='340' side='right'caption='[[7rww]]' scene=''> | + | <StructureSection load='7rww' size='340' side='right'caption='[[7rww]], [[Resolution|resolution]] 1.70Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RWW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RWW FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7rww]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RWW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RWW FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7rww FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7rww OCA], [https://pdbe.org/7rww PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7rww RCSB], [https://www.ebi.ac.uk/pdbsum/7rww PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7rww ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7rww FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7rww OCA], [https://pdbe.org/7rww PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7rww RCSB], [https://www.ebi.ac.uk/pdbsum/7rww PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7rww ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/C562_ECOLX C562_ECOLX] Electron-transport protein of unknown function. | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Herein we describe a designed protein building block whose self-assembly behaviour is dually gated by the redox state of disulphide bonds and the identity of exogenous metal ions. This protein construct is shown - through extensive structural and biophysical characterization - to access five distinct oligomeric states, exemplifying how the complex interplay between hydrophobic, metal-ligand, and reversible covalent interactions could be harnessed to obtain multiple, responsive protein architectures from a single building block. | ||
| + | |||
| + | Redox- and metal-directed structural diversification in designed metalloprotein assemblies.,Kakkis A, Golub E, Choi TS, Tezcan FA Chem Commun (Camb). 2022 Jun 16;58(49):6958-6961. doi: 10.1039/d2cc02440c. PMID:35642584<ref>PMID:35642584</ref> | ||
| + | |||
| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 7rww" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Cytochrome C 3D structures|Cytochrome C 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Escherichia coli]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Golub E]] |
| + | [[Category: Kakkis A]] | ||
Revision as of 07:46, 11 January 2023
Crystal structure of a Zn-bound RIDC1 variant
| |||||||||||
