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4qex

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==Crystal structure of PfEBA-175 RII in complex with a Fab fragment from inhibitory antibody R217==
==Crystal structure of PfEBA-175 RII in complex with a Fab fragment from inhibitory antibody R217==
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<StructureSection load='4qex' size='340' side='right' caption='[[4qex]], [[Resolution|resolution]] 4.50&Aring;' scene=''>
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<StructureSection load='4qex' size='340' side='right'caption='[[4qex]], [[Resolution|resolution]] 4.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4qex]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4k4m 4k4m]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QEX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QEX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4qex]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4k4m 4k4m]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QEX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QEX FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4k2u|4k2u]]</td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qex FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qex OCA], [https://pdbe.org/4qex PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qex RCSB], [https://www.ebi.ac.uk/pdbsum/4qex PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qex ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qex FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qex OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qex RCSB], [http://www.ebi.ac.uk/pdbsum/4qex PDBsum]</span></td></tr>
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</table>
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<table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q05644_PLAFA Q05644_PLAFA]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Structural and Functional Basis for Inhibition of Erythrocyte Invasion by Antibodies that Target Plasmodium falciparum EBA-175.,Chen E, Paing MM, Salinas N, Sim BK, Tolia NH PLoS Pathog. 2013 May;9(5):e1003390. doi: 10.1371/journal.ppat.1003390. Epub 2013, May 23. PMID:23717209<ref>PMID:23717209</ref>
Structural and Functional Basis for Inhibition of Erythrocyte Invasion by Antibodies that Target Plasmodium falciparum EBA-175.,Chen E, Paing MM, Salinas N, Sim BK, Tolia NH PLoS Pathog. 2013 May;9(5):e1003390. doi: 10.1371/journal.ppat.1003390. Epub 2013, May 23. PMID:23717209<ref>PMID:23717209</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4qex" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Antibody 3D structures|Antibody 3D structures]]
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*[[Erythrocyte binding antigen|Erythrocyte binding antigen]]
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*[[3D structures of non-human antibody|3D structures of non-human antibody]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Chen, E.]]
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[[Category: Plasmodium falciparum]]
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[[Category: Paing, M M.]]
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[[Category: Chen E]]
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[[Category: Salinas, N.]]
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[[Category: Paing MM]]
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[[Category: Sim, B K.]]
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[[Category: Salinas N]]
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[[Category: Tolia, N H.]]
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[[Category: Sim BK]]
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[[Category: Adhesion]]
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[[Category: Tolia NH]]
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[[Category: Antibody]]
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[[Category: Cell adhesion]]
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[[Category: Cell surface]]
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[[Category: Extrecellular]]
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[[Category: Immune system]]
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[[Category: Immunity]]
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[[Category: Immunoglobulin domain]]
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[[Category: Invasion]]
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[[Category: Ligand]]
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[[Category: Pfeba-175]]
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[[Category: Receptor]]
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Current revision

Crystal structure of PfEBA-175 RII in complex with a Fab fragment from inhibitory antibody R217

PDB ID 4qex

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