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2krk

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==Solution NMR Structure of 26S protease regulatory subunit 8 from H.sapiens, Northeast Structural Genomics Consortium Target Target HR3102A==
==Solution NMR Structure of 26S protease regulatory subunit 8 from H.sapiens, Northeast Structural Genomics Consortium Target Target HR3102A==
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<StructureSection load='2krk' size='340' side='right'caption='[[2krk]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2krk' size='340' side='right'caption='[[2krk]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2krk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KRK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KRK FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2krk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KRK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KRK FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PSMC5, SUG1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2krk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2krk OCA], [https://pdbe.org/2krk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2krk RCSB], [https://www.ebi.ac.uk/pdbsum/2krk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2krk ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2krk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2krk OCA], [https://pdbe.org/2krk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2krk RCSB], [https://www.ebi.ac.uk/pdbsum/2krk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2krk ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/PRS8_HUMAN PRS8_HUMAN]] The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex.
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[https://www.uniprot.org/uniprot/PRS8_HUMAN PRS8_HUMAN] The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Acton, T B]]
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[[Category: Acton TB]]
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[[Category: Ciccosanti, C]]
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[[Category: Ciccosanti C]]
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[[Category: Everett, J K]]
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[[Category: Everett JK]]
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[[Category: Janjua, J]]
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[[Category: Janjua J]]
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[[Category: Liu, G]]
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[[Category: Liu G]]
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[[Category: Montelione, G T]]
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[[Category: Montelione GT]]
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[[Category: Structural genomic]]
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[[Category: Nair R]]
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[[Category: Nair, R]]
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[[Category: Rost B]]
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[[Category: Rost, B]]
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[[Category: Shastry R]]
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[[Category: Shastry, R]]
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[[Category: Xiao R]]
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[[Category: Xiao, R]]
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[[Category: Acetylation]]
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[[Category: Atp-binding]]
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[[Category: Atp-dependent degradation]]
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[[Category: Cytoplasm]]
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[[Category: Nucleotide-binding]]
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[[Category: Nucleus]]
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[[Category: Polymorphism]]
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[[Category: Proteasome]]
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[[Category: Protein binding]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Target hr3102a]]
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Revision as of 08:47, 14 June 2023

Solution NMR Structure of 26S protease regulatory subunit 8 from H.sapiens, Northeast Structural Genomics Consortium Target Target HR3102A

PDB ID 2krk

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