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5cgn

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==Structure of quasiracemic Ala-Magainin 2 with a beta amino acid substitution at position 8==
==Structure of quasiracemic Ala-Magainin 2 with a beta amino acid substitution at position 8==
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<StructureSection load='5cgn' size='340' side='right' caption='[[5cgn]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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<StructureSection load='5cgn' size='340' side='right'caption='[[5cgn]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5cgn]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CGN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CGN FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5cgn]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CGN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5CGN FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=DGL:D-GLUTAMIC+ACID'>DGL</scene>, <scene name='pdbligand=DHI:D-HISTIDINE'>DHI</scene>, <scene name='pdbligand=DIL:D-ISOLEUCINE'>DIL</scene>, <scene name='pdbligand=DLE:D-LEUCINE'>DLE</scene>, <scene name='pdbligand=DLY:D-LYSINE'>DLY</scene>, <scene name='pdbligand=DPN:D-PHENYLALANINE'>DPN</scene>, <scene name='pdbligand=DSE:N-METHYL-D-SERINE'>DSE</scene>, <scene name='pdbligand=DSG:D-ASPARAGINE'>DSG</scene>, <scene name='pdbligand=DVA:D-VALINE'>DVA</scene>, <scene name='pdbligand=MED:D-METHIONINE'>MED</scene>, <scene name='pdbligand=XCP:(1S,2S)-2-AMINOCYCLOPENTANECARBOXYLIC+ACID'>XCP</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=DGL:D-GLUTAMIC+ACID'>DGL</scene>, <scene name='pdbligand=DHI:D-HISTIDINE'>DHI</scene>, <scene name='pdbligand=DIL:D-ISOLEUCINE'>DIL</scene>, <scene name='pdbligand=DLE:D-LEUCINE'>DLE</scene>, <scene name='pdbligand=DLY:D-LYSINE'>DLY</scene>, <scene name='pdbligand=DPN:D-PHENYLALANINE'>DPN</scene>, <scene name='pdbligand=DSE:N-METHYL-D-SERINE'>DSE</scene>, <scene name='pdbligand=DSG:D-ASPARAGINE'>DSG</scene>, <scene name='pdbligand=DVA:D-VALINE'>DVA</scene>, <scene name='pdbligand=MED:D-METHIONINE'>MED</scene>, <scene name='pdbligand=XCP:(1S,2S)-2-AMINOCYCLOPENTANECARBOXYLIC+ACID'>XCP</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5cgo|5cgo]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5cgn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cgn OCA], [https://pdbe.org/5cgn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5cgn RCSB], [https://www.ebi.ac.uk/pdbsum/5cgn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5cgn ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cgn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cgn OCA], [http://pdbe.org/5cgn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cgn RCSB], [http://www.ebi.ac.uk/pdbsum/5cgn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5cgn ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MAGA_XENLA MAGA_XENLA] Antimicrobial peptides that inhibit the growth of numerous species of bacteria and fungi and induce osmotic lysis of protozoa. Magainins are membrane lytic agents.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5cgn" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5cgn" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Magainin 2|Magainin 2]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Forest, K T]]
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[[Category: Large Structures]]
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[[Category: Gellman, S H]]
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[[Category: Synthetic construct]]
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[[Category: Hayouka, Z]]
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[[Category: Forest KT]]
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[[Category: Mortenson, D E]]
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[[Category: Gellman SH]]
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[[Category: Satyshur, K A]]
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[[Category: Hayouka Z]]
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[[Category: Thomas, N C]]
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[[Category: Mortenson DE]]
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[[Category: Weisblum, B]]
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[[Category: Satyshur KA]]
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[[Category: Antimicrobial]]
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[[Category: Thomas NC]]
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[[Category: Antimicrobial protein]]
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[[Category: Weisblum B]]
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[[Category: Beta amino acid]]
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[[Category: Homochiral dimerization]]
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[[Category: Quasiracemate]]
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Current revision

Structure of quasiracemic Ala-Magainin 2 with a beta amino acid substitution at position 8

PDB ID 5cgn

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