This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5ug4
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 5ug4 is ON HOLD Authors: Filippova, E.V., Minasov, G., Shuvalova, L., Kiryukhina, O., Anderson, W.F., Center for Structural Genomics of Infectious D...) |
|||
| (3 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Structure of spermidine N-acetyltransferase SpeG from Vibrio cholerae== | |
| + | <StructureSection load='5ug4' size='340' side='right'caption='[[5ug4]], [[Resolution|resolution]] 2.15Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5ug4]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_cholerae_O1 Vibrio cholerae O1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UG4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5UG4 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EOH:ETHANOL'>EOH</scene>, <scene name='pdbligand=MOH:METHANOL'>MOH</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ug4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ug4 OCA], [https://pdbe.org/5ug4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ug4 RCSB], [https://www.ebi.ac.uk/pdbsum/5ug4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ug4 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ATDA_VIBCH ATDA_VIBCH] Involved in the protection against polyamine toxicity by regulating their concentration. Catalyzes the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to the primary amino groups of spermidine to yield N(1)- and N(8)-acetylspermidine. It can use polyamines such as spermine and N(1)-acetylspermine, but not putrescine or cadaverine.<ref>PMID:23184347</ref> <ref>PMID:25623305</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Spermidine/spermine N-acetyltransferase|Spermidine/spermine N-acetyltransferase]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: Filippova | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Vibrio cholerae O1]] |
| - | [[Category: | + | [[Category: Anderson WF]] |
| - | [[Category: Shuvalova | + | [[Category: Filippova EV]] |
| + | [[Category: Kiryukhina O]] | ||
| + | [[Category: Minasov G]] | ||
| + | [[Category: Shuvalova L]] | ||
Current revision
Structure of spermidine N-acetyltransferase SpeG from Vibrio cholerae
| |||||||||||
