This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
7n9i
From Proteopedia
(Difference between revisions)
m (Protected "7n9i" [edit=sysop:move=sysop]) |
|||
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==1.4A Structure of Drosophila melanogaster Frataxin== | |
| + | <StructureSection load='7n9i' size='340' side='right'caption='[[7n9i]], [[Resolution|resolution]] 1.40Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[7n9i]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7N9I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7N9I FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7n9i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7n9i OCA], [https://pdbe.org/7n9i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7n9i RCSB], [https://www.ebi.ac.uk/pdbsum/7n9i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7n9i ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FRDA_DROME FRDA_DROME] Promotes the biosynthesis of heme as well as the assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways (PubMed:18540637). May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+) (PubMed:18540637). May be able to store large amounts of the metal in the form of a ferrihydrite mineral by oligomerization (PubMed:18540637). Required for ecdysteroidogenesis in the prothoracic gland which is necessary for larval to pupal transition (PubMed:25628335).<ref>PMID:18540637</ref> <ref>PMID:25628335</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Frataxin 3D Structures|Frataxin 3D Structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Drosophila melanogaster]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Brunzelle JS]] | ||
| + | [[Category: Stemmler TL]] | ||
Current revision
1.4A Structure of Drosophila melanogaster Frataxin
| |||||||||||
