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7dvk
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 7dvk is ON HOLD Authors: Description: Category: Unreleased Structures) |
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| - | '''Unreleased structure''' | ||
| - | + | ==PyrI4 in complex with intermolecular Diels-Alder product== | |
| - | + | <StructureSection load='7dvk' size='340' side='right'caption='[[7dvk]], [[Resolution|resolution]] 2.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7dvk]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_rugosporus Streptomyces rugosporus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DVK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DVK FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HOF:methyl+4-[[(1S,6S)-6-(dimethylcarbamoyl)cyclohex-2-en-1-yl]carbamoyloxymethyl]benzoate'>HOF</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7dvk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7dvk OCA], [https://pdbe.org/7dvk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7dvk RCSB], [https://www.ebi.ac.uk/pdbsum/7dvk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7dvk ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PYRI4_STRRG PYRI4_STRRG] Involved in the biosynthesis of the spirotetramate antibiotics pyrroindomycins. Catalyzes the intramolecular cyclization forming the spiro-conjugate moiety in pyrroindomycins, via an exo-selective [4+2] cycloaddition reaction.<ref>PMID:25730548</ref> <ref>PMID:26877021</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Streptomyces rugosporus]] | ||
| + | [[Category: Addlagatta A]] | ||
| + | [[Category: Kashyap R]] | ||
Current revision
PyrI4 in complex with intermolecular Diels-Alder product
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