1vty
From Proteopedia
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==Crystal structure of a Z-DNA fragment containing thymine/2-aminoadenine base pairs== | ==Crystal structure of a Z-DNA fragment containing thymine/2-aminoadenine base pairs== | ||
| - | <StructureSection load='1vty' size='340' side='right' caption='[[1vty]], [[Resolution|resolution]] 1.30Å' scene=''> | + | <StructureSection load='1vty' size='340' side='right'caption='[[1vty]], [[Resolution|resolution]] 1.30Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1vty]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VTY OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[1vty]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VTY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VTY FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1AP:2,6-DIAMINOPURINE+NUCLEOTIDE'>1AP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vty FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vty OCA], [https://pdbe.org/1vty PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vty RCSB], [https://www.ebi.ac.uk/pdbsum/1vty PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vty ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The Z-DNA structure has been shown to form in two crystals made from self-complementary DNA hexamers d(CGTDCG) and d(CDCGTG) which contain thymine/2-aminoadenine (TD) base pairs. The latter structure has been solved and refined to 1.3 A resolution and it shows only small conformational changes due to the introduction of the TD base pairs in comparison with the structure of d(CG)3. Spectroscopic studies with these compounds demonstrate that DNA molecules containing 2-aminoadenine residues form Z-DNA slightly more easily than do those containing adenine nucleotides, but not as readily as the parent sequence containing only guanine-cytosine base pairs. | ||
| + | |||
| + | Crystal structure of a Z-DNA fragment containing thymine/2-aminoadenine base pairs.,Coll M, Wang AH, van der Marel GA, van Boom JH, Rich A J Biomol Struct Dyn. 1986 Oct;4(2):157-72. doi: 10.1080/07391102.1986.10506337. PMID:3271437<ref>PMID:3271437</ref> | ||
| + | |||
| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 1vty" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Synthetic construct]] |
| - | [[Category: | + | [[Category: Coll M]] |
| - | [[Category: Rich | + | [[Category: Rich A]] |
| - | [[Category: | + | [[Category: Van Boom JH]] |
| - | [[Category: | + | [[Category: Van Der Marel GA]] |
| - | [[Category: | + | [[Category: Wang AH-J]] |
| - | + | ||
| - | + | ||
Current revision
Crystal structure of a Z-DNA fragment containing thymine/2-aminoadenine base pairs
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