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1f7t
From Proteopedia
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| - | [[Image:1f7t.png|left|200px]] | ||
| - | + | ==HOLO-(ACYL CARRIER PROTEIN) SYNTHASE AT 1.8A== | |
| - | + | <StructureSection load='1f7t' size='340' side='right'caption='[[1f7t]], [[Resolution|resolution]] 1.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1f7t]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F7T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1F7T FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE'>DTT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1f7t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f7t OCA], [https://pdbe.org/1f7t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1f7t RCSB], [https://www.ebi.ac.uk/pdbsum/1f7t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1f7t ProSAT]</span></td></tr> |
| - | [[1f7t]] is a 6 chain structure with sequence from [ | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ACPS_BACSU ACPS_BACSU] Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of fatty acid acyl-carrier-protein ACP. Also modifies the D-alanyl carrier protein but fails to recognize PCP and AcpK, an acyl carrier protein of secondary metabolism.<ref>PMID:11489886</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f7/1f7t_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1f7t ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
*[[Acyl carrier protein synthase|Acyl carrier protein synthase]] | *[[Acyl carrier protein synthase|Acyl carrier protein synthase]] | ||
| - | + | *[[Acyl carrier protein synthase 3D structures|Acyl carrier protein synthase 3D structures]] | |
| - | == | + | *[[Proteins from Mycobacterium tuberculosis|Proteins from Mycobacterium tuberculosis]] |
| - | < | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Bacillus subtilis]] | [[Category: Bacillus subtilis]] | ||
| - | [[Category: Fritz | + | [[Category: Large Structures]] |
| - | [[Category: Hixon | + | [[Category: Fritz CC]] |
| - | [[Category: Lin | + | [[Category: Hixon J]] |
| - | [[Category: Mathew | + | [[Category: Lin L]] |
| - | [[Category: Parris | + | [[Category: Mathew R]] |
| - | [[Category: Seehra | + | [[Category: Parris KD]] |
| - | [[Category: Somers | + | [[Category: Seehra J]] |
| - | [[Category: Stahl | + | [[Category: Somers WS]] |
| - | [[Category: Tam | + | [[Category: Stahl M]] |
| - | + | [[Category: Tam A]] | |
| - | + | ||
| - | + | ||
Current revision
HOLO-(ACYL CARRIER PROTEIN) SYNTHASE AT 1.8A
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Categories: Bacillus subtilis | Large Structures | Fritz CC | Hixon J | Lin L | Mathew R | Parris KD | Seehra J | Somers WS | Stahl M | Tam A
