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4ke2
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the hyperactive Type I antifreeze from winter flounder== | |
| + | <StructureSection load='4ke2' size='340' side='right'caption='[[4ke2]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4ke2]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudopleuronectes_americanus Pseudopleuronectes americanus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KE2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KE2 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ke2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ke2 OCA], [https://pdbe.org/4ke2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ke2 RCSB], [https://www.ebi.ac.uk/pdbsum/4ke2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ke2 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ANPM_PSEAM ANPM_PSEAM] Contributes to protect fish blood from freezing at subzero sea water temperatures. Lowers the blood freezing point by about 1.1 degrees at a concentration of 0.1 mg/ml, and by about 1.5 degrees at a concentration of 0.2 mg/ml. Binds to nascent ice crystals and prevents further growth.<ref>PMID:15141201</ref> <ref>PMID:15716269</ref> <ref>PMID:18225917</ref> <ref>PMID:24531972</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Antifreeze protein 3D structures|Antifreeze protein 3D structures]] | |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Pseudopleuronectes americanus]] | ||
| + | [[Category: Allingham JS]] | ||
| + | [[Category: Campbell RL]] | ||
| + | [[Category: Davies PL]] | ||
| + | [[Category: Lin F-H]] | ||
| + | [[Category: Sun T]] | ||
Current revision
Crystal structure of the hyperactive Type I antifreeze from winter flounder
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