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4quv
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4quv is ON HOLD until Paper Publication Authors: Li, X., Blobel, G. Description:) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of an integral membrane delta(14)-sterol reductase== | |
| - | + | <StructureSection load='4quv' size='340' side='right'caption='[[4quv]], [[Resolution|resolution]] 2.74Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4quv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methylotuvimicrobium_alcaliphilum_20Z Methylotuvimicrobium alcaliphilum 20Z]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QUV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QUV FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.743Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4quv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4quv OCA], [https://pdbe.org/4quv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4quv RCSB], [https://www.ebi.ac.uk/pdbsum/4quv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4quv ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ERG_META2 ERG_META2] Reduces the C14=C15 double bond of 4,4-dimethyl-cholesta-8,14,24-trienol to produce 4,4-dimethyl-cholesta-8,24-dienol. Complements the deletion of the Delta(14)-sterol reductase gene ERG24 in yeast.<ref>PMID:25307054</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Methylotuvimicrobium alcaliphilum 20Z]] | ||
| + | [[Category: Blobel G]] | ||
| + | [[Category: Li X]] | ||
Current revision
Structure of an integral membrane delta(14)-sterol reductase
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