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5t0i

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'''Unreleased structure'''
 
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The entry 5t0i is ON HOLD
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==Structural basis for dynamic regulation of the human 26S proteasome==
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<SX load='5t0i' size='340' side='right' viewer='molstar' caption='[[5t0i]], [[Resolution|resolution]] 8.00&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5t0i]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T0I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5T0I FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5t0i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t0i OCA], [https://pdbe.org/5t0i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5t0i RCSB], [https://www.ebi.ac.uk/pdbsum/5t0i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5t0i ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PRS7_HUMAN PRS7_HUMAN] The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. In case of HIV-1 infection, positive modulator of Tat-mediated transactivation.<ref>PMID:9295362</ref>
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Authors: Chen, S., Wu, J., Lu, Y., Ma, Y.B., Lee, B.H., Yu, Z., Ouyang, Q., Finley, D., Kirschner, M.W., Mao, Y.
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==See Also==
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*[[Proteasome 3D structures|Proteasome 3D structures]]
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Description: Structural basis for dynamic regulation of the human 26S proteasome
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== References ==
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[[Category: Unreleased Structures]]
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<references/>
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[[Category: Yu, Z]]
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__TOC__
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[[Category: Ouyang, Q]]
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</SX>
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[[Category: Lee, B.H]]
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[[Category: Homo sapiens]]
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[[Category: Mao, Y]]
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[[Category: Large Structures]]
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[[Category: Finley, D]]
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[[Category: Chen S]]
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[[Category: Ma, Y.B]]
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[[Category: Finley D]]
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[[Category: Kirschner, M.W]]
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[[Category: Kirschner MW]]
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[[Category: Lu, Y]]
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[[Category: Lee BH]]
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[[Category: Wu, J]]
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[[Category: Lu Y]]
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[[Category: Chen, S]]
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[[Category: Ma YB]]
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[[Category: Mao Y]]
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[[Category: Ouyang Q]]
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[[Category: Wu J]]
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[[Category: Yu Z]]

Current revision

Structural basis for dynamic regulation of the human 26S proteasome

5t0i, resolution 8.00Å

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OCA

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